CEACAM1 is a direct SOX10 target and inhibits melanoma immune infiltration and stemness

SOX10 is a key regulator of melanoma progression and promotes a melanocytic/differentiated state. Here we identified melanoma cell lines lacking SOX10 expression which retain their in vivo growth capabilities. More importantly, we find that SOX10 can regulate T-cell infiltration in melanoma while al...

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Detalles Bibliográficos
Autores principales: Abou-Hamad, John, Hodgins, Jonathan J., de Souza, Christiano T., Garland, Brennan, Labrèche, Cédrik, Marotel, Marie, Gibson, Cameron, Delisle, Samuel, Pascoal, Julia, Auer, Rebecca C., Ardolino, Michele, Sabourin, Luc A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9682343/
https://www.ncbi.nlm.nih.gov/pubmed/36437876
http://dx.doi.org/10.1016/j.isci.2022.105524

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