Cargando…
Effects of parasites coinfection with other pathogens on animal host: A literature review
A parasite-host relationship is complicated and largely remained poorly understood, especially when mixed infections involving pathogenic bacteria and viruses are present in the same host. It has been found that most parasites are able to manipulate the host’s immune responses to evade or overcome i...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Veterinary World
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9682395/ https://www.ncbi.nlm.nih.gov/pubmed/36425132 http://dx.doi.org/10.14202/vetworld.2022.2414-2424 |
_version_ | 1784834842841579520 |
---|---|
author | Hananeh, Wael M. Radhi, Asya Mukbel, Rami M. Ismail, Zuhair Bani |
author_facet | Hananeh, Wael M. Radhi, Asya Mukbel, Rami M. Ismail, Zuhair Bani |
author_sort | Hananeh, Wael M. |
collection | PubMed |
description | A parasite-host relationship is complicated and largely remained poorly understood, especially when mixed infections involving pathogenic bacteria and viruses are present in the same host. It has been found that most parasites are able to manipulate the host’s immune responses to evade or overcome its defense systems. Several mechanisms have been postulated that may explain this phenomenon in different animal species. Recent evidence suggests that coinfections involving many parasitic species alter the host’s vulnerability to other microorganisms, hinder diagnostic accuracy, and may negatively impact vaccination by altering the host’s immune responsiveness. The objective of this review was to provide a comprehensive summary of the current understanding of how parasites interact with other pathogens in different animal species. A better understanding of this complex relationship will aid in the improvement efforts of disease diagnosis, treatment, and control measures such as novel and effective vaccines and therapeutics for infectious diseases. |
format | Online Article Text |
id | pubmed-9682395 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Veterinary World |
record_format | MEDLINE/PubMed |
spelling | pubmed-96823952022-11-23 Effects of parasites coinfection with other pathogens on animal host: A literature review Hananeh, Wael M. Radhi, Asya Mukbel, Rami M. Ismail, Zuhair Bani Vet World Review Article A parasite-host relationship is complicated and largely remained poorly understood, especially when mixed infections involving pathogenic bacteria and viruses are present in the same host. It has been found that most parasites are able to manipulate the host’s immune responses to evade or overcome its defense systems. Several mechanisms have been postulated that may explain this phenomenon in different animal species. Recent evidence suggests that coinfections involving many parasitic species alter the host’s vulnerability to other microorganisms, hinder diagnostic accuracy, and may negatively impact vaccination by altering the host’s immune responsiveness. The objective of this review was to provide a comprehensive summary of the current understanding of how parasites interact with other pathogens in different animal species. A better understanding of this complex relationship will aid in the improvement efforts of disease diagnosis, treatment, and control measures such as novel and effective vaccines and therapeutics for infectious diseases. Veterinary World 2022-10 2022-10-15 /pmc/articles/PMC9682395/ /pubmed/36425132 http://dx.doi.org/10.14202/vetworld.2022.2414-2424 Text en Copyright: © Hananeh, et al. https://creativecommons.org/licenses/by/4.0/Open Access. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Review Article Hananeh, Wael M. Radhi, Asya Mukbel, Rami M. Ismail, Zuhair Bani Effects of parasites coinfection with other pathogens on animal host: A literature review |
title | Effects of parasites coinfection with other pathogens on animal host: A literature review |
title_full | Effects of parasites coinfection with other pathogens on animal host: A literature review |
title_fullStr | Effects of parasites coinfection with other pathogens on animal host: A literature review |
title_full_unstemmed | Effects of parasites coinfection with other pathogens on animal host: A literature review |
title_short | Effects of parasites coinfection with other pathogens on animal host: A literature review |
title_sort | effects of parasites coinfection with other pathogens on animal host: a literature review |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9682395/ https://www.ncbi.nlm.nih.gov/pubmed/36425132 http://dx.doi.org/10.14202/vetworld.2022.2414-2424 |
work_keys_str_mv | AT hananehwaelm effectsofparasitescoinfectionwithotherpathogensonanimalhostaliteraturereview AT radhiasya effectsofparasitescoinfectionwithotherpathogensonanimalhostaliteraturereview AT mukbelramim effectsofparasitescoinfectionwithotherpathogensonanimalhostaliteraturereview AT ismailzuhairbani effectsofparasitescoinfectionwithotherpathogensonanimalhostaliteraturereview |