Cargando…
Huntingtin regulates calcium fluxes in skeletal muscle
The expression of the Huntingtin protein, well known for its involvement in the neurodegenerative Huntington’s disease, has been confirmed in skeletal muscle. The impact of HTT deficiency was studied in human skeletal muscle cell lines and in a mouse model with inducible and muscle-specific HTT dele...
Autores principales: | Chivet, Mathilde, McCluskey, Maximilian, Nicot, Anne Sophie, Brocard, Julie, Beaufils, Mathilde, Giovannini, Diane, Giannesini, Benoit, Poreau, Brice, Brocard, Jacques, Humbert, Sandrine, Saudou, Frédéric, Fauré, Julien, Marty, Isabelle |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9682417/ https://www.ncbi.nlm.nih.gov/pubmed/36409218 http://dx.doi.org/10.1085/jgp.202213103 |
Ejemplares similares
-
Deletion of the microtubule-associated protein 6 (MAP6) results in skeletal muscle dysfunction
por: Sébastien, Muriel, et al.
Publicado: (2018) -
In vivo RyR1 reduction in muscle triggers a core-like myopathy
por: Pelletier, Laurent, et al.
Publicado: (2020) -
Huntingtin recruits KIF1A to transport synaptic vesicle precursors along the mouse axon to support synaptic transmission and motor skill learning
por: Vitet, Hélène, et al.
Publicado: (2023) -
Calcineurin and huntingtin form a calcium-sensing machinery that directs neurotrophic signals to the nucleus
por: Scaramuzzino, Chiara, et al.
Publicado: (2022) -
Dynamics of triadin, a muscle-specific triad protein, within sarcoplasmic reticulum subdomains
por: Sébastien, Muriel, et al.
Publicado: (2020)