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Evolution of self-sustained circadian rhythms is facilitated by seasonal change of daylight

Self-sustained oscillation is a fundamental property of circadian rhythms and has been repeatedly tested since the early days of circadian research, resulting in the discovery of almost all organisms possessing self-sustained circadian oscillations. However, the evolutionary advantage of self-sustai...

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Autores principales: Seki, Motohide, Ito, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9682437/
https://www.ncbi.nlm.nih.gov/pubmed/36416042
http://dx.doi.org/10.1098/rspb.2022.0577
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author Seki, Motohide
Ito, Hiroshi
author_facet Seki, Motohide
Ito, Hiroshi
author_sort Seki, Motohide
collection PubMed
description Self-sustained oscillation is a fundamental property of circadian rhythms and has been repeatedly tested since the early days of circadian research, resulting in the discovery of almost all organisms possessing self-sustained circadian oscillations. However, the evolutionary advantage of self-sustainability has been only speculatively discussed. In this theoretical study, we sought the environmental constraints and selection pressure that drive the acquisition or degeneration of self-sustainability through the process of evolution. We considered the dynamics of a gene regulatory network having a light input pathway under 12 h light and 12 h dark cycles or multiple day length conditions and then optimized the network structure using an evolutionary algorithm. By designing the fitness function in the evolutionary algorithm, we investigated the environmental conditions that led to the evolution of the self-sustained oscillators. Then, we found that self-sustained oscillation is rarer than damped oscillation and hourglass-type behaviour. Moreover, networks with self-sustainability have a markedly high fitness score when we assume that a network has to generate a constantly periodic expression profile regardless of day length. This study is, to our knowledge, the first to show that seasonality facilitated the evolution of the self-sustained circadian clock, which was consistent with empirical records.
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spelling pubmed-96824372022-11-30 Evolution of self-sustained circadian rhythms is facilitated by seasonal change of daylight Seki, Motohide Ito, Hiroshi Proc Biol Sci Evolution Self-sustained oscillation is a fundamental property of circadian rhythms and has been repeatedly tested since the early days of circadian research, resulting in the discovery of almost all organisms possessing self-sustained circadian oscillations. However, the evolutionary advantage of self-sustainability has been only speculatively discussed. In this theoretical study, we sought the environmental constraints and selection pressure that drive the acquisition or degeneration of self-sustainability through the process of evolution. We considered the dynamics of a gene regulatory network having a light input pathway under 12 h light and 12 h dark cycles or multiple day length conditions and then optimized the network structure using an evolutionary algorithm. By designing the fitness function in the evolutionary algorithm, we investigated the environmental conditions that led to the evolution of the self-sustained oscillators. Then, we found that self-sustained oscillation is rarer than damped oscillation and hourglass-type behaviour. Moreover, networks with self-sustainability have a markedly high fitness score when we assume that a network has to generate a constantly periodic expression profile regardless of day length. This study is, to our knowledge, the first to show that seasonality facilitated the evolution of the self-sustained circadian clock, which was consistent with empirical records. The Royal Society 2022-11-30 2022-11-23 /pmc/articles/PMC9682437/ /pubmed/36416042 http://dx.doi.org/10.1098/rspb.2022.0577 Text en © 2022 The Authors. https://creativecommons.org/licenses/by/4.0/Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, provided the original author and source are credited.
spellingShingle Evolution
Seki, Motohide
Ito, Hiroshi
Evolution of self-sustained circadian rhythms is facilitated by seasonal change of daylight
title Evolution of self-sustained circadian rhythms is facilitated by seasonal change of daylight
title_full Evolution of self-sustained circadian rhythms is facilitated by seasonal change of daylight
title_fullStr Evolution of self-sustained circadian rhythms is facilitated by seasonal change of daylight
title_full_unstemmed Evolution of self-sustained circadian rhythms is facilitated by seasonal change of daylight
title_short Evolution of self-sustained circadian rhythms is facilitated by seasonal change of daylight
title_sort evolution of self-sustained circadian rhythms is facilitated by seasonal change of daylight
topic Evolution
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9682437/
https://www.ncbi.nlm.nih.gov/pubmed/36416042
http://dx.doi.org/10.1098/rspb.2022.0577
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