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Structural and Mechanistic Investigation of the Unusual Metabolism of Nifurtimox
[Image: see text] The oral antiparasitic drug nifurtimox has been used to treat Chagas disease for more than 50 years. Historical studies determined that very little nifurtimox is excreted unchanged, but contemporaneous preclinical studies of radiolabeled nifurtimox found almost all of the radiolabe...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9682525/ https://www.ncbi.nlm.nih.gov/pubmed/36209416 http://dx.doi.org/10.1021/acs.chemrestox.2c00210 |