Cargando…

Identification of the mitochondrial protein ADCK2 as a therapeutic oncotarget of NSCLC

The aarF domain containing kinase 2 (ADCK2) is a mitochondria-locating protein, important for fatty acid metabolism and coenzyme Q biosynthesis. The bioinformatics results show that elevated ADCK2 transcripts in NSCLC correlate with poor overall survival and poor anti-PD-1/PD-L1 therapy response. AD...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Jin-zhi, Liu, Jia, Xu, Yi-xin, Pu, Wang-yang, Shen, Ming-jing, Jiang, Kan-qiu, Yang, Yi-ling, Lu, Jingjing, Deng, Zhengbo, Yang, Yi, Xu, Wei-hua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9682539/ https://www.ncbi.nlm.nih.gov/pubmed/36439873 http://dx.doi.org/10.7150/ijbs.78354

Ejemplares similares

ADCK1 is a potential therapeutic target of osteosarcoma
por: Zhuo, Bao-biao, et al.
Publicado: (2022)

The inflammasome: an emerging therapeutic oncotarget for cancer prevention
por: Zhiyu, Wang, et al.
Publicado: (2016)

Glutathione peroxidases as oncotargets
por: Jiao, Yang, et al.
Publicado: (2017)

Drosophila ADCK1 is critical for maintaining mitochondrial structures and functions in the muscle
por: Yoon, Woongchang, et al.
Publicado: (2019)

Calorie Restriction Rescues Mitochondrial Dysfunction in Adck2-Deficient Skeletal Muscle
por: Hernández-Camacho, Juan Diego, et al.
Publicado: (2022)

Identification of matrix-remodeling associated 5 as a possible molecular oncotarget of pancreatic cancer
por: Peng, Shi-qing, et al.
Publicado: (2023)

Introducing, OncoTarget
Publicado: (2010)

Hexokinase 2 as oncotarget
por: Patra, Krushna C., et al.
Publicado: (2013)

Deubiquitinating enzymes as oncotargets
por: McClurg, Urszula L., et al.
Publicado: (2015)

MKK3 as oncotarget
por: Bossi, Gianluca
Publicado: (2016)

Akt-Girdin as oncotarget
por: Takahashi, Masahide, et al.
Publicado: (2015)

Eph receptors as oncotargets
por: Charmsaz, Sara, et al.
Publicado: (2017)

P62: An emerging oncotarget for osteolytic metastasis
por: Zhang, Jing, et al.
Publicado: (2016)

A Gly-Zipper Motif Mediates Homodimerization of the Transmembrane Domain of the Mitochondrial Kinase ADCK3
por: Khadria, Ambalika S., et al.
Publicado: (2014)

Caveolin-1, a stress-related oncotarget, in drug resistance
por: Wang, Zhiyu, et al.
Publicado: (2015)

YAP as oncotarget in uveal melanoma
por: Yu, Fa-Xing, et al.
Publicado: (2014)

ADCK2 Haploinsufficiency Reduces Mitochondrial Lipid Oxidation and Causes Myopathy Associated with CoQ Deficiency
por: Vázquez-Fonseca, Luis, et al.
Publicado: (2019)

PHF5A as a new OncoTarget and therapeutic prospects
por: Li, Xiaojiang, et al.
Publicado: (2023)

Breathing the air of mitochondrial respiration via an important oncotarget - mitochondrial glycerophosphate dehydrogenase (mGPDH)
por: Thakur, Shilpa, et al.
Publicado: (2019)

ADCK1 activates the β-catenin/TCF signaling pathway to promote the growth and migration of colon cancer cells
por: Ji, Yong, et al.
Publicado: (2021)

Galectin-1 as an oncotarget in gliomas and melanomas
por: Lefranc, Florence, et al.
Publicado: (2011)

Invasive leader cells: metastatic oncotarget
por: Cheung, Kevin J., et al.
Publicado: (2014)

IRAK1: oncotarget in MDS and AML
por: Beverly, Levi J., et al.
Publicado: (2014)

Bruton's tyrosine kinase: oncotarget in myeloma
por: Tai, Yu-Tzu, et al.
Publicado: (2012)

DNp73: oncotarget in invasion and metastasis
por: Pützer, Brigitte M.
Publicado: (2013)

AXL is an oncotarget in human colorectal cancer
por: Martinelli, Erika, et al.
Publicado: (2015)

Oncotargeting G proteins: The Hippo in the room
por: Feng, Xiaodong, et al.
Publicado: (2014)

4E-BP1 as an oncotarget
por: She, Qing-Bai
Publicado: (2015)

Librarians against scientists: Oncotarget’s lesson
por: Blagosklonny, Mikhail V.
Publicado: (2018)

Early-onset of ADCK4 glomerulopathy with renal failure: a case report
por: Lolin, Ksenija, et al.
Publicado: (2017)

ADCK2 Knockdown Affects the Migration of Melanoma Cells via MYL6
por: Vierthaler, Marlene, et al.
Publicado: (2022)

AarF Domain Containing Kinase 3 (ADCK3) Mutant Cells Display Signs of Oxidative Stress, Defects in Mitochondrial Homeostasis and Lysosomal Accumulation
por: Cullen, Jason K., et al.
Publicado: (2016)

Liposomes and nanotechnology in drug development: focus on oncotargets
por: Kozako, Tomohiro, et al.
Publicado: (2012)

Addendum: Librarians against scientists: Oncotarget’s lesson
por: Blagosklonny, Mikhail V.
Publicado: (2018)

An integrated approach identifies new oncotargets in melanoma
por: Cecconi, Daniela, et al.
Publicado: (2017)

Neuropeptide G Protein-Coupled Receptors as Oncotargets
por: Moody, Terry W., et al.
Publicado: (2018)

HPV: Immunology lessons from an ancient oncotarget
por: Krishna, Sri, et al.
Publicado: (2019)

Coenzyme Q10 supplementation therapy for 2 children with proteinuria renal disease and ADCK4 mutation: Case reports and literature review
por: Feng, Chunyue, et al.
Publicado: (2017)

Targeting a ribonucleoprotein complex containing the caprin-1 protein and the c-Myc mRNA suppresses tumor growth in mice: an identification of a novel oncotarget
por: Qiu, Ya-Qi, et al.
Publicado: (2014)

Correction: AarF Domain Containing Kinase 3 (ADCK3) Mutant Cells Display Signs of Oxidative Stress, Defects in Mitochondrial Homeostasis and Lysosomal Accumulation
por: Cullen, Jason K., et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_imkgj6h18j4534ps4t5h6tv6et