Cargando…

Stearoyl-CoA Desaturase-1 dependent lipid droplets accumulation in cancer-associated fibroblasts facilitates the progression of lung cancer

Rationale: Cancer-associated fibroblasts (CAFs) are the main components in the tumor microenvironment (TME) and facilitate lung cancer progression. Studies have reported that metabolic reprogramming can regulate the function of CAFs, especially abnormal lipid metabolism. Lipid droplets (LDs) are ubi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Yana, Gu, Zhuoyu, Wan, Jiajia, Lou, Xiaohan, Liu, Shuangqing, Wang, Yuan, Bian, Yangyang, Wang, Fei, Li, Zhenzhen, Qin, Zhihai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9682541/ https://www.ncbi.nlm.nih.gov/pubmed/36439884 http://dx.doi.org/10.7150/ijbs.74924

Ejemplares similares

Regulation of lipid droplet size and phospholipid composition by stearoyl-CoA desaturase
por: Shi, Xun, et al.
Publicado: (2013)

Stearoyl-CoA Desaturase Is Essential for Porcine Adipocyte Differentiation
por: Liu, Lulu, et al.
Publicado: (2020)

Stearoyl-CoA desaturase 1 regulates malignant progression of cervical cancer cells
por: Wang, Lingling, et al.
Publicado: (2022)

The Evolutionary Pattern and the Regulation of Stearoyl-CoA Desaturase Genes
por: Wu, Xiaoyun, et al.
Publicado: (2013)

Role of Stearoyl-CoA Desaturase 1 in Cardiovascular Physiology
por: Balatskyi, Volodymyr V., et al.
Publicado: (2023)

Targeting stearoyl-CoA desaturase 1 to repress endometrial cancer progression
por: Li, Weihua, et al.
Publicado: (2018)

Stearoyl-CoA Desaturase 1 as a Therapeutic Target for the Treatment of Cancer
por: Tracz-Gaszewska, Zuzanna, et al.
Publicado: (2019)

Mechanisms of stearoyl CoA desaturase inhibitor sensitivity and acquired resistance in cancer
por: Oatman, Nicole, et al.
Publicado: (2021)

The evolutionary history of the stearoyl-CoA desaturase gene family in vertebrates
por: Castro, L Filipe C, et al.
Publicado: (2011)

Elevated Stearoyl-CoA Desaturase in Brains of Patients with Alzheimer's Disease
por: Astarita, Giuseppe, et al.
Publicado: (2011)

X-ray Structure of a Mammalian Stearoyl-CoA Desaturase
por: Bai, Yonghong, et al.
Publicado: (2015)

Discovery of Tumor-Specific Irreversible Inhibitors of Stearoyl CoA Desaturase
por: Theodoropoulos, Panayotis C., et al.
Publicado: (2016)

Stearoyl-CoA Desaturase-2 in Murine Development, Metabolism, and Disease
por: O’Neill, Lucas M., et al.
Publicado: (2020)

PDGF‐induced fibroblast growth requires monounsaturated fatty acid production by stearoyl‐CoA desaturase
por: Coomans de Brachène, Alexandra, et al.
Publicado: (2017)

Loss of stearoyl-CoA desaturase 2 disrupts inflammatory response in macrophages
por: Lin, Joseph B., et al.
Publicado: (2023)

Stearoyl-CoA desaturase-1 is a key factor for lung cancer-initiating cells
por: Noto, A, et al.
Publicado: (2013)

Increased expression of the gene encoding stearoyl-CoA desaturase 1 in human bladder cancer
por: Presler, M., et al.
Publicado: (2018)

Stearoyl-CoA Desaturase 1 as a Therapeutic Biomarker: Focusing on Cancer Stem Cells
por: Min, Jin-Young, et al.
Publicado: (2023)

Stearoyl-CoA Desaturase Regulates Angiogenesis and Energy Metabolism in Ischemic Cardiomyocytes
por: Gan, Ana-Maria, et al.
Publicado: (2022)

Oleic acid from cancer-associated fibroblast promotes cancer cell stemness by stearoyl-CoA desaturase under glucose-deficient condition
por: Hwang, Sung-Hyun, et al.
Publicado: (2022)

Stearoyl-CoA desaturase-1 mediated cell apoptosis in colorectal cancer by promoting ceramide synthesis
por: Chen, Ling, et al.
Publicado: (2016)

Stearoyl-CoA desaturase-1 promotes colorectal cancer metastasis in response to glucose by suppressing PTEN
por: Ran, Hui, et al.
Publicado: (2018)

A hint from zebrafish models of hepatic tumorigenesis: Targeting stearoyl-CoA desaturase
por: Lv, Kunpeng, et al.
Publicado: (2019)

Regulation of stearoyl-CoA desaturase-1 after central and peripheral nerve lesions
por: Breuer, Sebastian, et al.
Publicado: (2004)

Stearoyl-CoA desaturase-1 impairs the reparative properties of macrophages and microglia in the brain
por: Bogie, Jeroen F.J., et al.
Publicado: (2020)

Free ferrous ions sustain activity of mammalian stearoyl-CoA desaturase-1
por: Shen, Jiemin, et al.
Publicado: (2023)

Free ferrous ions sustain activity of mammalian stearoyl-CoA desaturase-1
por: Shen, Jiemin, et al.
Publicado: (2023)

Stearoyl-CoA Desaturase 1 Potentiates Hypoxic plus Nutrient-Deprived Pancreatic Cancer Cell Ferroptosis Resistance
por: Gao, Jie, et al.
Publicado: (2021)

Stearoyl-CoA Desaturase-1: Is It the Link between Sulfur Amino Acids and Lipid Metabolism?
por: Poloni, Soraia, et al.
Publicado: (2015)

Fatty Liver Is Associated with Transcriptional Downregulation of Stearoyl-CoA Desaturase and Impaired Protein Dimerization
por: Fernández Gianotti, Tomas, et al.
Publicado: (2013)

Global deficiency of stearoyl-CoA desaturase-2 protects against diet-induced adiposity
por: O’Neill, Lucas M., et al.
Publicado: (2020)

Stearoyl-CoA Desaturase-Mediated Monounsaturated Fatty Acid Availability Supports Humoral Immunity
por: Zhou, Xian, et al.
Publicado: (2021)

A Brain-Penetrant Stearoyl-CoA Desaturase Inhibitor Reverses α-Synuclein Toxicity
por: Nuber, Silke, et al.
Publicado: (2022)

Lipidomics profiling of goose granulosa cell model of stearoyl-CoA desaturase function identifies a pattern of lipid droplets associated with follicle development
por: Yuan, Xin, et al.
Publicado: (2021)

Inhibition of Stearoyl-CoA Desaturase 1 Expression Induces CHOP-Dependent Cell Death in Human Cancer Cells
por: Minville-Walz, Mélaine, et al.
Publicado: (2010)

Inhibition of stearoyl CoA desaturase‐1 activity suppresses tumour progression and improves prognosis in human bladder cancer
por: Piao, Chiyuan, et al.
Publicado: (2018)

Stearoyl CoA Desaturase Is Essential for Regulation of Endoplasmic Reticulum Homeostasis and Tumor Growth in Glioblastoma Cancer Stem Cells
por: Pinkham, Kelsey, et al.
Publicado: (2019)

miR-215 Inhibits Colorectal Cancer Cell Migration and Invasion via Targeting Stearoyl-CoA Desaturase
por: Xu, Xinhua, et al.
Publicado: (2020)

Stearoyl-CoA desaturase 1 and paracrine diffusible signals have a major role in the promotion of breast cancer cell migration induced by cancer-associated fibroblasts
por: Angelucci, C, et al.
Publicado: (2015)

Depletion of stearoyl-CoA desaturase ( scd) leads to fatty liver disease and defective mating behavior in zebrafish
por: Xu, Shan-Shan, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_haen92g1s8cpq34hiqc2ko1q6e