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A Late Presentation of COVID-19 Induced Bowel Ischemia

INTRODUCTION: Infection with COVID-19 may lead to extrapulmonary pathologies secondary to the systemic inflammatory effects of the virus. CASE DESCRIPTION: This case report discusses a 55-year-old female patient who presented with small bowel obstruction (SBO) several months after resolution of a CO...

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Autores principales: Annabi, Hani Michael, Dodson, Darrel, Applebaum, Bruce, Clapp, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society of Laparoscopic and Robotic Surgeons 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9682609/
https://www.ncbi.nlm.nih.gov/pubmed/36452880
http://dx.doi.org/10.4293/CRSLS.2022.00057
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author Annabi, Hani Michael
Dodson, Darrel
Applebaum, Bruce
Clapp, Benjamin
author_facet Annabi, Hani Michael
Dodson, Darrel
Applebaum, Bruce
Clapp, Benjamin
author_sort Annabi, Hani Michael
collection PubMed
description INTRODUCTION: Infection with COVID-19 may lead to extrapulmonary pathologies secondary to the systemic inflammatory effects of the virus. CASE DESCRIPTION: This case report discusses a 55-year-old female patient who presented with small bowel obstruction (SBO) several months after resolution of a COVID-19 infection. The patient was surgically treated with a small bowel resection, and eventually made a full recovery. DISCUSSION: The pathophysiology of COVID-19-induced SBO can be explained by the prolonged inflammation and coagulation activation in the bowel’s vasculature system. Under these circumstances, microthrombosis occurs in the bowel’s microvasculature; the affected intestinal tissue becomes ischemic and infarcted. The damaged bowel is eventually replaced with fibrotic scar tissue, thus promoting bowel stricture and subsequent obstruction. CONCLUSION: COVID-19 can be responsible for both acute and chronic embolic and thrombotic events in the mesenteric vasculature, which acts as a risk factor in the manifestation of SBO.
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spelling pubmed-96826092022-11-29 A Late Presentation of COVID-19 Induced Bowel Ischemia Annabi, Hani Michael Dodson, Darrel Applebaum, Bruce Clapp, Benjamin CRSLS Case Report INTRODUCTION: Infection with COVID-19 may lead to extrapulmonary pathologies secondary to the systemic inflammatory effects of the virus. CASE DESCRIPTION: This case report discusses a 55-year-old female patient who presented with small bowel obstruction (SBO) several months after resolution of a COVID-19 infection. The patient was surgically treated with a small bowel resection, and eventually made a full recovery. DISCUSSION: The pathophysiology of COVID-19-induced SBO can be explained by the prolonged inflammation and coagulation activation in the bowel’s vasculature system. Under these circumstances, microthrombosis occurs in the bowel’s microvasculature; the affected intestinal tissue becomes ischemic and infarcted. The damaged bowel is eventually replaced with fibrotic scar tissue, thus promoting bowel stricture and subsequent obstruction. CONCLUSION: COVID-19 can be responsible for both acute and chronic embolic and thrombotic events in the mesenteric vasculature, which acts as a risk factor in the manifestation of SBO. Society of Laparoscopic and Robotic Surgeons 2022-11-22 /pmc/articles/PMC9682609/ /pubmed/36452880 http://dx.doi.org/10.4293/CRSLS.2022.00057 Text en © 2022 by SLS, Society of Laparoscopic & Robotic Surgeons. https://creativecommons.org/licenses/by-nc-sa/3.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-ShareAlike 3.0 Unported license (http://creativecommons.org/licenses/by-nc-sa/3.0/ (https://creativecommons.org/licenses/by-nc-sa/3.0/) ), which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Case Report
Annabi, Hani Michael
Dodson, Darrel
Applebaum, Bruce
Clapp, Benjamin
A Late Presentation of COVID-19 Induced Bowel Ischemia
title A Late Presentation of COVID-19 Induced Bowel Ischemia
title_full A Late Presentation of COVID-19 Induced Bowel Ischemia
title_fullStr A Late Presentation of COVID-19 Induced Bowel Ischemia
title_full_unstemmed A Late Presentation of COVID-19 Induced Bowel Ischemia
title_short A Late Presentation of COVID-19 Induced Bowel Ischemia
title_sort late presentation of covid-19 induced bowel ischemia
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9682609/
https://www.ncbi.nlm.nih.gov/pubmed/36452880
http://dx.doi.org/10.4293/CRSLS.2022.00057
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