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Forebrain-specific conditional calcineurin deficiency induces dentate gyrus immaturity and hyper-dopaminergic signaling in mice
Calcineurin (Cn), a phosphatase important for synaptic plasticity and neuronal development, has been implicated in the etiology and pathophysiology of neuropsychiatric disorders, including schizophrenia, intellectual disability, autism spectrum disorders, epilepsy, and Alzheimer’s disease. Forebrain...
Autores principales: | Hagihara, Hideo, Shoji, Hirotaka, Kuroiwa, Mahomi, Graef, Isabella A., Crabtree, Gerald R., Nishi, Akinori, Miyakawa, Tsuyoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9682671/ https://www.ncbi.nlm.nih.gov/pubmed/36414974 http://dx.doi.org/10.1186/s13041-022-00981-0 |
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