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ALKBH5 in mouse testicular Sertoli cells regulates Cdh2 mRNA translation to maintain blood–testis barrier integrity

BACKGROUND: RNA N(6)-methyladenosine (m(6)A) is involved in mammalian spermatogenesis. In both germ cells and Leydig cells, ALKBH5 regulates spermatogenesis and androgen synthesis in an m(6)A-dependent manner. However, it is unclear whether ALKBH5 plays a role in testicular Sertoli cells, which cons...

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Detalles Bibliográficos
Autores principales: Cai, Zhonglin, Zhang, Yao, Yang, Lin, Ma, Chunhui, Fei, Yi, Ding, Jing, Song, Wei, Tong, Wei-Min, Niu, Yamei, Li, Hongjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9682758/
https://www.ncbi.nlm.nih.gov/pubmed/36418936
http://dx.doi.org/10.1186/s11658-022-00404-x

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