The immunological mechanisms and therapeutic potential in drug-induced liver injury: lessons learned from acetaminophen hepatotoxicity

Acute liver failure caused by drug overdose is a significant clinical problem in developed countries. Acetaminophen (APAP), a widely used analgesic and antipyretic drug, but its overdose can cause acute liver failure. In addition to APAP-induced direct hepatotoxicity, the intracellular signaling mec...

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Detalles Bibliográficos
Autores principales: Li, Qianhui, Chen, Feng, Wang, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9682794/
https://www.ncbi.nlm.nih.gov/pubmed/36414987
http://dx.doi.org/10.1186/s13578-022-00921-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9682794/
https://www.ncbi.nlm.nih.gov/pubmed/36414987
http://dx.doi.org/10.1186/s13578-022-00921-4

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