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Mupirocin blocks imiquimod-induced psoriasis-like skin lesion by inhibiting epidermal isoleucyl-tRNA synthetase

BACKGROUND: The Isoleucyl-tRNA synthetase (IARS) catalyzes isoleucine to the corresponding tRNA, maintaining the accuracy of gene translation. Its role in psoriasis has been not investigated so far. In this study, we aimed to investigate the mechanisms underlying the efficacy of IARS inhibitor, mupi...

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Detalles Bibliográficos
Autores principales:	Yan, Bing-Xi, Chen, Xue-Yan, Wang, Zhao-Yuan, Cui, Ying-Zhe, Landeck, Lilla, Fu, Ni-Chang, Yang, Xing-Yu, Xu, Fan, Zhou, Yuan, Chen, Jia-Qi, Man, Xiao-Yong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9682813/ https://www.ncbi.nlm.nih.gov/pubmed/36419191 http://dx.doi.org/10.1186/s12964-022-00995-0

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