Can the triumph of mRNA vaccines against COVID-19 be extended to other viral infections of humans and domesticated animals?

The unprecedented success of mRNA vaccines in managing the COVID-19 pandemic raises the prospect of applying the mRNA platform to other viral diseases of humans and domesticated animals, which may lead to more efficacious vaccines for some agents. We briefly discuss reasons why mRNA vaccines achieve...

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Detalles Bibliográficos
Autores principales: Sehrawat, Sharvan, Osterrieder, Nikolaus, Schmid, D. Scott, Rouse, Barry T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Institut Pasteur. Published by Elsevier Masson SAS. 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9682868/
https://www.ncbi.nlm.nih.gov/pubmed/36435367
http://dx.doi.org/10.1016/j.micinf.2022.105078
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author Sehrawat, Sharvan
Osterrieder, Nikolaus
Schmid, D. Scott
Rouse, Barry T.
author_facet Sehrawat, Sharvan
Osterrieder, Nikolaus
Schmid, D. Scott
Rouse, Barry T.
author_sort Sehrawat, Sharvan
collection PubMed
description The unprecedented success of mRNA vaccines in managing the COVID-19 pandemic raises the prospect of applying the mRNA platform to other viral diseases of humans and domesticated animals, which may lead to more efficacious vaccines for some agents. We briefly discuss reasons why mRNA vaccines achieved such success against COVID-19 and indicate what other virus infections and disease conditions might also be ripe for control using mRNA vaccines. We also evaluate situations where mRNA could prove valuable to rebalance the status of immune responsiveness and achieve success as a therapeutic vaccine approach against infections that induce immunoinflammatory lesions.
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spelling pubmed-96828682022-11-23 Can the triumph of mRNA vaccines against COVID-19 be extended to other viral infections of humans and domesticated animals? Sehrawat, Sharvan Osterrieder, Nikolaus Schmid, D. Scott Rouse, Barry T. Microbes Infect Review The unprecedented success of mRNA vaccines in managing the COVID-19 pandemic raises the prospect of applying the mRNA platform to other viral diseases of humans and domesticated animals, which may lead to more efficacious vaccines for some agents. We briefly discuss reasons why mRNA vaccines achieved such success against COVID-19 and indicate what other virus infections and disease conditions might also be ripe for control using mRNA vaccines. We also evaluate situations where mRNA could prove valuable to rebalance the status of immune responsiveness and achieve success as a therapeutic vaccine approach against infections that induce immunoinflammatory lesions. Institut Pasteur. Published by Elsevier Masson SAS. 2023 2022-11-23 /pmc/articles/PMC9682868/ /pubmed/36435367 http://dx.doi.org/10.1016/j.micinf.2022.105078 Text en © 2022 Institut Pasteur. Published by Elsevier Masson SAS. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Review
Sehrawat, Sharvan
Osterrieder, Nikolaus
Schmid, D. Scott
Rouse, Barry T.
Can the triumph of mRNA vaccines against COVID-19 be extended to other viral infections of humans and domesticated animals?
title Can the triumph of mRNA vaccines against COVID-19 be extended to other viral infections of humans and domesticated animals?
title_full Can the triumph of mRNA vaccines against COVID-19 be extended to other viral infections of humans and domesticated animals?
title_fullStr Can the triumph of mRNA vaccines against COVID-19 be extended to other viral infections of humans and domesticated animals?
title_full_unstemmed Can the triumph of mRNA vaccines against COVID-19 be extended to other viral infections of humans and domesticated animals?
title_short Can the triumph of mRNA vaccines against COVID-19 be extended to other viral infections of humans and domesticated animals?
title_sort can the triumph of mrna vaccines against covid-19 be extended to other viral infections of humans and domesticated animals?
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9682868/
https://www.ncbi.nlm.nih.gov/pubmed/36435367
http://dx.doi.org/10.1016/j.micinf.2022.105078
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