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The H240R Protein of African Swine Fever Virus Inhibits Interleukin 1β Production by Inhibiting NEMO Expression and NLRP3 Oligomerization

The H240R protein (pH240R), encoded by the H240R gene of African swine fever virus (ASFV), is a 241-amino-acid capsid protein. We previously showed that the deletion of H240R from the ASFV genome, creating ASFV-ΔH240R, resulted in an approximately 2-log decrease in infectious virus production compar...

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Detalles Bibliográficos
Autores principales:	Zhou, Pingping, Dai, Jingwen, Zhang, Kehui, Wang, Tao, Li, Lian-Feng, Luo, Yuzi, Sun, Yuan, Qiu, Hua-Ji, Li, Su
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2022
Materias:	Virus-Cell Interactions
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9683016/ https://www.ncbi.nlm.nih.gov/pubmed/36326277 http://dx.doi.org/10.1128/jvi.00954-22

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