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Transcriptomic analysis of isolated and pooled human postmortem cerebellar Purkinje cells in autism spectrum disorders

At present, the neuronal mechanisms underlying the diagnosis of autism spectrum disorder (ASD) have not been established. However, studies from human postmortem ASD brains have consistently revealed disruptions in cerebellar circuitry, specifically reductions in Purkinje cell (PC) number and size. A...

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Detalles Bibliográficos
Autores principales:	Brandenburg, Cheryl, Griswold, Anthony J., Van Booven, Derek J., Kilander, Michaela B. C., Frei, Jeannine A., Nestor, Michael W., Dykxhoorn, Derek M., Pericak-Vance, Margaret A., Blatt, Gene J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9683032/ https://www.ncbi.nlm.nih.gov/pubmed/36437953 http://dx.doi.org/10.3389/fgene.2022.944837

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