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MTNet: A combined diagnosis algorithm of vessel segmentation and diabetic retinopathy for retinal images

Medical studies have shown that the condition of human retinal vessels may reveal the physiological structure of the relationship between age-related macular degeneration, glaucoma, atherosclerosis, cataracts, diabetic retinopathy, and other ophthalmic diseases and systemic diseases, and their abnor...

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Autores principales: Liu, Ruochen, Gao, Song, Zhang, Hengsheng, Wang, Simin, Zhou, Lun, Liu, Jiaming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9683560/
https://www.ncbi.nlm.nih.gov/pubmed/36417405
http://dx.doi.org/10.1371/journal.pone.0278126
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author Liu, Ruochen
Gao, Song
Zhang, Hengsheng
Wang, Simin
Zhou, Lun
Liu, Jiaming
author_facet Liu, Ruochen
Gao, Song
Zhang, Hengsheng
Wang, Simin
Zhou, Lun
Liu, Jiaming
author_sort Liu, Ruochen
collection PubMed
description Medical studies have shown that the condition of human retinal vessels may reveal the physiological structure of the relationship between age-related macular degeneration, glaucoma, atherosclerosis, cataracts, diabetic retinopathy, and other ophthalmic diseases and systemic diseases, and their abnormal changes often serve as a diagnostic basis for the severity of the condition. In this paper, we design and implement a deep learning-based algorithm for automatic segmentation of retinal vessel (CSP_UNet). It mainly adopts a U-shaped structure composed of an encoder and a decoder and utilizes a cross-stage local connectivity mechanism, attention mechanism, and multi-scale fusion, which can obtain better segmentation results with limited data set capacity. The experimental results show that compared with several existing classical algorithms, the proposed algorithm has the highest blood vessel intersection ratio on the dataset composed of four retinal fundus images, reaching 0.6674. Then, based on the CSP_UNet and introducing hard parameter sharing in multi-task learning, we innovatively propose a combined diagnosis algorithm vessel segmentation and diabetic retinopathy for retinal images (MTNet). The experiments show that the diagnostic accuracy of the MTNet algorithm is higher than that of the single task, with 0.4% higher vessel segmentation IoU and 5.2% higher diagnostic accuracy of diabetic retinopathy classification.
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spelling pubmed-96835602022-11-24 MTNet: A combined diagnosis algorithm of vessel segmentation and diabetic retinopathy for retinal images Liu, Ruochen Gao, Song Zhang, Hengsheng Wang, Simin Zhou, Lun Liu, Jiaming PLoS One Research Article Medical studies have shown that the condition of human retinal vessels may reveal the physiological structure of the relationship between age-related macular degeneration, glaucoma, atherosclerosis, cataracts, diabetic retinopathy, and other ophthalmic diseases and systemic diseases, and their abnormal changes often serve as a diagnostic basis for the severity of the condition. In this paper, we design and implement a deep learning-based algorithm for automatic segmentation of retinal vessel (CSP_UNet). It mainly adopts a U-shaped structure composed of an encoder and a decoder and utilizes a cross-stage local connectivity mechanism, attention mechanism, and multi-scale fusion, which can obtain better segmentation results with limited data set capacity. The experimental results show that compared with several existing classical algorithms, the proposed algorithm has the highest blood vessel intersection ratio on the dataset composed of four retinal fundus images, reaching 0.6674. Then, based on the CSP_UNet and introducing hard parameter sharing in multi-task learning, we innovatively propose a combined diagnosis algorithm vessel segmentation and diabetic retinopathy for retinal images (MTNet). The experiments show that the diagnostic accuracy of the MTNet algorithm is higher than that of the single task, with 0.4% higher vessel segmentation IoU and 5.2% higher diagnostic accuracy of diabetic retinopathy classification. Public Library of Science 2022-11-23 /pmc/articles/PMC9683560/ /pubmed/36417405 http://dx.doi.org/10.1371/journal.pone.0278126 Text en © 2022 Liu et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Liu, Ruochen
Gao, Song
Zhang, Hengsheng
Wang, Simin
Zhou, Lun
Liu, Jiaming
MTNet: A combined diagnosis algorithm of vessel segmentation and diabetic retinopathy for retinal images
title MTNet: A combined diagnosis algorithm of vessel segmentation and diabetic retinopathy for retinal images
title_full MTNet: A combined diagnosis algorithm of vessel segmentation and diabetic retinopathy for retinal images
title_fullStr MTNet: A combined diagnosis algorithm of vessel segmentation and diabetic retinopathy for retinal images
title_full_unstemmed MTNet: A combined diagnosis algorithm of vessel segmentation and diabetic retinopathy for retinal images
title_short MTNet: A combined diagnosis algorithm of vessel segmentation and diabetic retinopathy for retinal images
title_sort mtnet: a combined diagnosis algorithm of vessel segmentation and diabetic retinopathy for retinal images
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9683560/
https://www.ncbi.nlm.nih.gov/pubmed/36417405
http://dx.doi.org/10.1371/journal.pone.0278126
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