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MTNet: A combined diagnosis algorithm of vessel segmentation and diabetic retinopathy for retinal images
Medical studies have shown that the condition of human retinal vessels may reveal the physiological structure of the relationship between age-related macular degeneration, glaucoma, atherosclerosis, cataracts, diabetic retinopathy, and other ophthalmic diseases and systemic diseases, and their abnor...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9683560/ https://www.ncbi.nlm.nih.gov/pubmed/36417405 http://dx.doi.org/10.1371/journal.pone.0278126 |
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author | Liu, Ruochen Gao, Song Zhang, Hengsheng Wang, Simin Zhou, Lun Liu, Jiaming |
author_facet | Liu, Ruochen Gao, Song Zhang, Hengsheng Wang, Simin Zhou, Lun Liu, Jiaming |
author_sort | Liu, Ruochen |
collection | PubMed |
description | Medical studies have shown that the condition of human retinal vessels may reveal the physiological structure of the relationship between age-related macular degeneration, glaucoma, atherosclerosis, cataracts, diabetic retinopathy, and other ophthalmic diseases and systemic diseases, and their abnormal changes often serve as a diagnostic basis for the severity of the condition. In this paper, we design and implement a deep learning-based algorithm for automatic segmentation of retinal vessel (CSP_UNet). It mainly adopts a U-shaped structure composed of an encoder and a decoder and utilizes a cross-stage local connectivity mechanism, attention mechanism, and multi-scale fusion, which can obtain better segmentation results with limited data set capacity. The experimental results show that compared with several existing classical algorithms, the proposed algorithm has the highest blood vessel intersection ratio on the dataset composed of four retinal fundus images, reaching 0.6674. Then, based on the CSP_UNet and introducing hard parameter sharing in multi-task learning, we innovatively propose a combined diagnosis algorithm vessel segmentation and diabetic retinopathy for retinal images (MTNet). The experiments show that the diagnostic accuracy of the MTNet algorithm is higher than that of the single task, with 0.4% higher vessel segmentation IoU and 5.2% higher diagnostic accuracy of diabetic retinopathy classification. |
format | Online Article Text |
id | pubmed-9683560 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-96835602022-11-24 MTNet: A combined diagnosis algorithm of vessel segmentation and diabetic retinopathy for retinal images Liu, Ruochen Gao, Song Zhang, Hengsheng Wang, Simin Zhou, Lun Liu, Jiaming PLoS One Research Article Medical studies have shown that the condition of human retinal vessels may reveal the physiological structure of the relationship between age-related macular degeneration, glaucoma, atherosclerosis, cataracts, diabetic retinopathy, and other ophthalmic diseases and systemic diseases, and their abnormal changes often serve as a diagnostic basis for the severity of the condition. In this paper, we design and implement a deep learning-based algorithm for automatic segmentation of retinal vessel (CSP_UNet). It mainly adopts a U-shaped structure composed of an encoder and a decoder and utilizes a cross-stage local connectivity mechanism, attention mechanism, and multi-scale fusion, which can obtain better segmentation results with limited data set capacity. The experimental results show that compared with several existing classical algorithms, the proposed algorithm has the highest blood vessel intersection ratio on the dataset composed of four retinal fundus images, reaching 0.6674. Then, based on the CSP_UNet and introducing hard parameter sharing in multi-task learning, we innovatively propose a combined diagnosis algorithm vessel segmentation and diabetic retinopathy for retinal images (MTNet). The experiments show that the diagnostic accuracy of the MTNet algorithm is higher than that of the single task, with 0.4% higher vessel segmentation IoU and 5.2% higher diagnostic accuracy of diabetic retinopathy classification. Public Library of Science 2022-11-23 /pmc/articles/PMC9683560/ /pubmed/36417405 http://dx.doi.org/10.1371/journal.pone.0278126 Text en © 2022 Liu et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Liu, Ruochen Gao, Song Zhang, Hengsheng Wang, Simin Zhou, Lun Liu, Jiaming MTNet: A combined diagnosis algorithm of vessel segmentation and diabetic retinopathy for retinal images |
title | MTNet: A combined diagnosis algorithm of vessel segmentation and diabetic retinopathy for retinal images |
title_full | MTNet: A combined diagnosis algorithm of vessel segmentation and diabetic retinopathy for retinal images |
title_fullStr | MTNet: A combined diagnosis algorithm of vessel segmentation and diabetic retinopathy for retinal images |
title_full_unstemmed | MTNet: A combined diagnosis algorithm of vessel segmentation and diabetic retinopathy for retinal images |
title_short | MTNet: A combined diagnosis algorithm of vessel segmentation and diabetic retinopathy for retinal images |
title_sort | mtnet: a combined diagnosis algorithm of vessel segmentation and diabetic retinopathy for retinal images |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9683560/ https://www.ncbi.nlm.nih.gov/pubmed/36417405 http://dx.doi.org/10.1371/journal.pone.0278126 |
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