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Application of combined CRISPR screening for genetic and chemical-genetic interaction profiling in Mycobacterium tuberculosis

CRISPR screening, including CRISPR interference (CRISPRi) and CRISPR-knockout (CRISPR-KO) screening, has become a powerful technology in the genetic screening of eukaryotes. In contrast with eukaryotes, CRISPR-KO screening has not yet been applied to functional genomics studies in bacteria. Here, we...

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Detalles Bibliográficos
Autores principales:	Yan, Mei-Yi, Zheng, Dandan, Li, Si-Shang, Ding, Xin-Yuan, Wang, Chun-Liang, Guo, Xiao-Peng, Zhan, Lingjun, Jin, Qi, Yang, Jian, Sun, Yi-Cheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2022
Materias:	Biomedicine and Life Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9683719/ https://www.ncbi.nlm.nih.gov/pubmed/36417506 http://dx.doi.org/10.1126/sciadv.add5907

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