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Widespread hypertranscription in aggressive human cancers
Cancers are often defined by the dysregulation of specific transcriptional programs; however, the importance of global transcriptional changes is less understood. Hypertranscription is the genome-wide increase in RNA output. Hypertranscription’s prevalence, underlying drivers, and prognostic signifi...
Autores principales: | Zatzman, Matthew, Fuligni, Fabio, Ripsman, Ryan, Suwal, Tannu, Comitani, Federico, Edward, Lisa-Monique, Denroche, Rob, Jang, Gun Ho, Notta, Faiyaz, Gallinger, Steven, Selvanathan, Saravana P., Toretsky, Jeffrey A., Hellmann, Matthew D., Tabori, Uri, Huang, Annie, Shlien, Adam |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9683723/ https://www.ncbi.nlm.nih.gov/pubmed/36417526 http://dx.doi.org/10.1126/sciadv.abn0238 |
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