Protection against SARS-CoV-2 Omicron BA.1 variant challenge in macaques by prime-boost vaccination with Ad26.COV2.S and SpFN

Emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants and waning immunity call for next-generation vaccine strategies. Here, we assessed the immunogenicity and protective efficacy of two SARS-CoV-2 vaccines targeting the WA1/2020 spike protein, Ad26.COV2.S (Ad26) and Spike f...

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Detalles Bibliográficos
Autores principales: Yu, Jingyou, Thomas, Paul V., McMahan, Katherine, Jacob-Dolan, Catherine, Liu, Jinyan, He, Xuan, Hope, David, Martinez, Elizabeth J., Chen, Wei-Hung, Sciacca, Michaela, Hachmann, Nicole P., Lifton, Michelle, Miller, Jessica, Powers, Olivia C., Hall, Kevin, Wu, Cindy, Barrett, Julia, Swafford, Isabella, Currier, Jeffrey R., King, Jocelyn, Corbitt, Courtney, Chang, William C., Golub, Emily, Rees, Phyllis A., Peterson, Caroline E., Hajduczki, Agnes, Hussin, Elizabeth, Lange, Camille, Gong, Hua, Matyas, Gary R., Rao, Mangala, Paquin-Proulx, Dominic, Gromowski, Gregory D., Lewis, Mark G., Andersen, Hanne, Davis-Gardner, Meredith, Suthar, Mehul S., Michael, Nelson L., Bolton, Diane L., Joyce, M. Gordon, Modjarrad, Kayvon, Barouch, Dan H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9683731/
https://www.ncbi.nlm.nih.gov/pubmed/36417525
http://dx.doi.org/10.1126/sciadv.ade4433

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