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Soluble T-cadherin promotes pancreatic β-cell proliferation by upregulating Notch signaling

Endogenous humoral factors that link systemic and/or local insulin demand to pancreatic β-cells have not been identified. Here, we demonstrated that T-cadherin, a unique glycosylphosphatidylinositol-anchored cadherin primarily expressed in vascular endothelial cells and cardiac and skeletal muscle c...

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Detalles Bibliográficos
Autores principales: Okita, Tomonori, Kita, Shunbun, Fukuda, Shiro, Fukuoka, Keita, Kawada-Horitani, Emi, Iioka, Masahito, Nakamura, Yuto, Fujishima, Yuya, Nishizawa, Hitoshi, Kawamori, Dan, Matsuoka, Taka-aki, Norikazu, Maeda, Shimomura, Iichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9684056/
https://www.ncbi.nlm.nih.gov/pubmed/36439986
http://dx.doi.org/10.1016/j.isci.2022.105404