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Soluble T-cadherin promotes pancreatic β-cell proliferation by upregulating Notch signaling
Endogenous humoral factors that link systemic and/or local insulin demand to pancreatic β-cells have not been identified. Here, we demonstrated that T-cadherin, a unique glycosylphosphatidylinositol-anchored cadherin primarily expressed in vascular endothelial cells and cardiac and skeletal muscle c...
Autores principales: | Okita, Tomonori, Kita, Shunbun, Fukuda, Shiro, Fukuoka, Keita, Kawada-Horitani, Emi, Iioka, Masahito, Nakamura, Yuto, Fujishima, Yuya, Nishizawa, Hitoshi, Kawamori, Dan, Matsuoka, Taka-aki, Norikazu, Maeda, Shimomura, Iichiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9684056/ https://www.ncbi.nlm.nih.gov/pubmed/36439986 http://dx.doi.org/10.1016/j.isci.2022.105404 |
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