Single-cell profiling of vascular endothelial cells reveals progressive organ-specific vulnerabilities during obesity

Obesity promotes diverse pathologies, including atherosclerosis and dementia, which frequently involve vascular defects and endothelial cell (EC) dysfunction. Each organ has distinct EC subtypes, but whether ECs are differentially affected by obesity is unknown. Here we use single-cell RNA sequencin...

Descripción completa

Detalles Bibliográficos
Autores principales: Bondareva, Olga, Rodríguez-Aguilera, Jesús Rafael, Oliveira, Fabiana, Liao, Longsheng, Rose, Alina, Gupta, Anubhuti, Singh, Kunal, Geier, Florian, Schuster, Jenny, Boeckel, Jes-Niels, Buescher, Joerg M., Kohli, Shrey, Klöting, Nora, Isermann, Berend, Blüher, Matthias, Sheikh, Bilal N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9684070/
https://www.ncbi.nlm.nih.gov/pubmed/36400935
http://dx.doi.org/10.1038/s42255-022-00674-x

Ejemplares similares

Ejemplares similares