ADRA1A–Gα(q) signalling potentiates adipocyte thermogenesis through CKB and TNAP

Noradrenaline (NA) regulates cold-stimulated adipocyte thermogenesis(1). Aside from cAMP signalling downstream of β-adrenergic receptor activation, how NA promotes thermogenic output is still not fully understood. Here, we show that coordinated α(1)-adrenergic receptor (AR) and β(3)-AR signalling in...

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Detalles Bibliográficos
Autores principales: Rahbani, Janane F., Scholtes, Charlotte, Lagarde, Damien M., Hussain, Mohammed F., Roesler, Anna, Dykstra, Christien B., Bunk, Jakub, Samborska, Bozena, O’Brien, Shannon L., Tripp, Emma, Pacis, Alain, Angueira, Anthony R., Johansen, Olivia S., Cinkornpumin, Jessica, Hossain, Ishtiaque, Lynes, Matthew D., Zhang, Yang, White, Andrew P., Pastor, William A., Chondronikola, Maria, Sidossis, Labros, Klein, Samuel, Kralli, Anastasia, Cypess, Aaron M., Pedersen, Steen B., Jessen, Niels, Tseng, Yu-Hua, Gerhart-Hines, Zachary, Seale, Patrick, Calebiro, Davide, Giguère, Vincent, Kazak, Lawrence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9684074/
https://www.ncbi.nlm.nih.gov/pubmed/36344764
http://dx.doi.org/10.1038/s42255-022-00667-w

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