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Smc5/6’s multifaceted DNA binding capacities stabilize branched DNA structures

Smc5/6 is an evolutionarily conserved SMC complex with roles in DNA replication and repair, as well as in viral DNA restriction. Understanding its multiple functions has been hampered by a lack of mechanistic studies on how the Smc5/6 complex associates with different types of DNA. Here we address t...

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Detalles Bibliográficos
Autores principales: Chang, Jeremy T-H., Li, Shibai, Beckwitt, Emily C., Than, Thane, Haluska, Cory, Chandanani, Joshua, O’Donnell, Michael E., Zhao, Xiaolan, Liu, Shixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9684126/
https://www.ncbi.nlm.nih.gov/pubmed/36418314
http://dx.doi.org/10.1038/s41467-022-34928-9