Expanding cross-presenting dendritic cells enhances oncolytic virotherapy and is critical for long-term anti-tumor immunity

Immunotherapies directly enhancing anti-tumor CD8(+) T cell responses have yielded measurable but limited success, highlighting the need for alternatives. Anti-tumor T cell responses critically depend on antigen presenting dendritic cells (DC), and enhancing mobilization, antigen loading and activat...

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Detalles Bibliográficos
Autores principales: Svensson-Arvelund, Judit, Cuadrado-Castano, Sara, Pantsulaia, Gvantsa, Kim, Kristy, Aleynick, Mark, Hammerich, Linda, Upadhyay, Ranjan, Yellin, Michael, Marsh, Henry, Oreper, Daniel, Jhunjhunwala, Suchit, Moussion, Christine, Merad, Miriam, Brown, Brian D., García-Sastre, Adolfo, Brody, Joshua D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9684150/
https://www.ncbi.nlm.nih.gov/pubmed/36418317
http://dx.doi.org/10.1038/s41467-022-34791-8

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