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Dissecting Human Gonadal Cell Lineage Specification and Sex Determination Using A Single-cell RNA-seq Approach
Gonadal somatic cells are the main players in gonad development and are important for sex determination and germ cell development. Here, using a time-series single-cell RNA sequencing (scRNA-seq) strategy, we analyzed fetal germ cells (FGCs) and gonadal somatic cells in human embryos and fetuses. Cl...
Autores principales: | Wang, Rui, Liu, Xixi, Li, Li, Yang, Ming, Yong, Jun, Zhai, Fan, Wen, Lu, Yan, Liying, Qiao, Jie, Tang, Fuchou |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9684167/ https://www.ncbi.nlm.nih.gov/pubmed/35513251 http://dx.doi.org/10.1016/j.gpb.2022.04.002 |
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