Cargando…

Thrombin generation assays to personalize treatment in bleeding and thrombotic diseases

Treatment of bleeding and thrombotic disorders is highly standardized and based on evidence-based medicine guidelines. These evidence-based treatment schemes are well accepted but may lead to either insufficient treatment or over-dosing, because the individuals’ hemostatic properties are not taken i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Valke, Lars L. F. G., Rijpma, Sanna, Meijer, Danielle, Schols, Saskia E. M., van Heerde, Waander L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Cardiovascular Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9684194/ https://www.ncbi.nlm.nih.gov/pubmed/36440026 http://dx.doi.org/10.3389/fcvm.2022.1033416

Ejemplares similares

Fibrinolytic assays in bleeding of unknown cause: Improvement in diagnostic yield
por: Valke, Lars L. F. G., et al.
Publicado: (2022)

Pharmacodynamic monitoring of factor VIII replacement therapy in hemophilia A: Combining thrombin and plasmin generation
por: Valke, Lars L.F.G., et al.
Publicado: (2020)

Combining factor VIII levels and thrombin/plasmin generation: A population pharmacokinetic‐pharmacodynamic model for patients with haemophilia A
por: Bukkems, Laura H., et al.
Publicado: (2022)

In patients with hemophilia, a decreased thrombin generation profile is associated with a severe bleeding phenotype
por: Verhagen, Marieke J.A., et al.
Publicado: (2023)

Thrombin generation for monitoring hemostatic therapy in hemophilia A: A narrative review
por: Verhagen, Marieke J. A., et al.
Publicado: (2022)

Semi-automated thrombin dynamics applying the ST Genesia thrombin generation assay
por: Carlo, Audrey, et al.
Publicado: (2022)

Automated Thrombin Generation Assay for Rivaroxaban, Apixaban, and Edoxaban Measurements
por: Meihandoest, Tamana, et al.
Publicado: (2021)

Circulating Small Extracellular Vesicles Profiling and Thrombin Generation as Potential Markers of Thrombotic Risk in Glioma Patients
por: Melnichnikova, Olga, et al.
Publicado: (2022)

Thrombin and plasmin generation in patients with plasminogen or plasminogen activator inhibitor type 1 deficiency
por: Saes, Joline L., et al.
Publicado: (2019)

Application of the thrombin generation assay in patients with antiphospholipid syndrome: A systematic review of the literature
por: Gehlen, Rachel, et al.
Publicado: (2023)

Editorial: Advances in thrombin generation
por: de Laat-Kremers, Romy, et al.
Publicado: (2023)

Thrombin Generation as a Method to Identify the Risk of Bleeding in High Clinical-Risk Patients Using Dual Antiplatelet Therapy
por: de Breet, C. P. D. M., et al.
Publicado: (2021)

Investigation of thrombin generation assay to predict vaso-occlusive crisis in adulthood with sickle cell disease
por: Feugray, Guillaume, et al.
Publicado: (2022)

Serpins in Hemostasis as Therapeutic Targets for Bleeding or Thrombotic Disorders
por: Bianchini, Elsa P., et al.
Publicado: (2021)

Diagnostic work up of patients with increased bleeding tendency
por: Zegers, Suzanne A. M., et al.
Publicado: (2019)

Ex vivo reversal of effects of rivaroxaban evaluated using thromboelastometry and thrombin generation assay
por: Schenk, B., et al.
Publicado: (2016)

Intrinsic coagulation pathway-mediated thrombin generation in mouse whole blood
por: Konrath, Sandra, et al.
Publicado: (2022)

Assessing the individual roles of FII, FV, and FX activity in the thrombin generation process
por: Bai, Cuicui, et al.
Publicado: (2022)

Hemoclot Thrombin Inhibitor Assay and Expected Peak-Trough Levels of Dabigatran: A Multicenter Study
por: Liu, Zhiyan, et al.
Publicado: (2022)

Patients With Multiple Myeloma Have a Disbalanced Whole Blood Thrombin Generation Profile
por: Li, Li, et al.
Publicado: (2022)

Increased Clot Formation in the Absence of Increased Thrombin Generation in Patients with Peripheral Arterial Disease: A Case–Control Study
por: Kleinegris, Marie-Claire F., et al.
Publicado: (2017)

Associations of anaemia with bleeding and thrombotic complications in patients with atrial fibrillation treated with warfarin: a registry-based nested case–control study
por: Helin, Tuukka Antero, et al.
Publicado: (2023)

Thrombotic risk assessment in antiphospholipid syndrome: the role of new antibody specificities and thrombin generation assay
por: Sciascia, Savino, et al.
Publicado: (2016)

Serial thrombin generation and exploration of alternative anticoagulants in critically ill COVID-19 patients: Observations from Maastricht Intensive Care COVID Cohort
por: van de Berg, Tom W., et al.
Publicado: (2022)

Bleeding and thrombotic complications during treatment with direct oral anticoagulants or vitamin K antagonists in venous thromboembolic patients included in the prospective, observational START2-register
por: Palareti, Gualtiero, et al.
Publicado: (2020)

Treatment of patients with rare bleeding disorders in the Netherlands: Real‐life data from the RBiN study
por: Maas, Dominique P. M. S. M., et al.
Publicado: (2022)

Clinical use of thrombin generation assays
por: Binder, Nikolaus B., et al.
Publicado: (2021)

Benefits of Thromboelastography and Thrombin Generation Assay for Bleeding Prediction in Patients With Thrombocytopenia or Hematologic Malignancies
por: Kim, Seon Young, et al.
Publicado: (2017)

Cancer and Thrombotic Risk: The Platelet Paradigm
por: Lee, Elizabeth C., et al.
Publicado: (2017)

Galectin-3 Mediates Thrombin-Induced Vascular Smooth Muscle Cell Migration
por: Tian, Lei, et al.
Publicado: (2021)

The role of monocytes in thrombotic diseases: a review
por: Han, Zhongyu, et al.
Publicado: (2023)

Effects of Heparin and Bivalirudin on Thrombin-Induced Platelet Activation: Differential Modulation of PAR Signaling Drives Divergent Prothrombotic Responses
por: Lund, Mikael, et al.
Publicado: (2021)

Activation of Inflammatory and Pro-Thrombotic Pathways in Acute Stress Cardiomyopathy
por: Fitzgibbons, Timothy P., et al.
Publicado: (2017)

Platelets and Antiplatelet Medication in COVID-19-Related Thrombotic Complications
por: Schrottmaier, Waltraud C., et al.
Publicado: (2022)

Vaccine-induced immune thrombotic thrombocytopenia: Updates in pathobiology and diagnosis
por: Jevtic, Stefan D., et al.
Publicado: (2022)

Appropriate Anti-Thrombotic/Anti-Thrombin Therapy for Thrombotic Lesions
por: Iqbal, Zafar, et al.
Publicado: (2012)

PC Deficiency Testing: Thrombin-Thrombomodulin as PC Activator and Aptamer-Based Enzyme Capturing Increase Diagnostic Accuracy
por: Reda, Sara, et al.
Publicado: (2021)

Sex Differences in Clinical Characteristics and Prognosis in Primary Thrombotic Antiphospholipid Syndrome
por: Huang, Yongfa, et al.
Publicado: (2022)

A Case-Control Study of the Dose-Response Relationship Between Thrombin Activatable Fibrinolysis Inhibitor and Acute Myocardial Infarction
por: Zhao, Mengnan, et al.
Publicado: (2022)

Thrombotic events with or without thrombocytopenia in recipients of adenovirus-based COVID-19 vaccines
por: Cari, Luigi, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_tmm9c11v34scgtcsrkvglt6gnj