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Bim Deletion Reduces Functional Deficits Following Ischemic Stroke in Association with Modulation of Apoptosis and Inflammation

Cellular apoptosis is a key pathological mechanism contributing to neuronal death following ischemic stroke. The pro-apoptotic Bcl-2 family protein, Bim, is an important regulator of apoptosis. In this study we investigated the effect of Bim expression on post-stroke functional outcomes, brain injur...

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Detalles Bibliográficos
Autores principales:	Glab, Jason A., Puthalakath, Hamsa, Zhang, Shenpeng R., Vinh, Antony, Drummond, Grant R., Sobey, Christopher G., De Silva, T. Michael, Kim, Hyun Ah
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2022
Materias:	Original Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9684233/ https://www.ncbi.nlm.nih.gov/pubmed/35149957 http://dx.doi.org/10.1007/s12017-022-08703-4

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