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HSP70 alleviates sepsis-induced cardiomyopathy by attenuating mitochondrial dysfunction-initiated NLRP3 inflammasome-mediated pyroptosis in cardiomyocytes

BACKGROUND: Sepsis-induced cardiomyopathy (SIC) is an identified serious complication of sepsis that is associated with adverse outcomes and high mortality. Heat shock proteins (HSPs) have been implicated in suppressing septic inflammation. The aim of this study was to investigate whether HSP70 can...

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Detalles Bibliográficos
Autores principales: Song, Chenlu, Zhang, Yiqiu, Pei, Qing, Zheng, Li, Wang, Meiyu, Shi, Youzhen, Wu, Shan, Ni, Wei, Fu, Xiujun, Peng, Yinbo, Zhang, Wen, Yao, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9684341/
https://www.ncbi.nlm.nih.gov/pubmed/36439706
http://dx.doi.org/10.1093/burnst/tkac043