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Copper-coated hospital surfaces: reduction of total bacterial loads and resistant Acinetobacter spp.

Healthcare-associated infections (HAIs) represent a global challenge and an even more staggering concern when related to microorganisms capable of resisting and surviving for long periods in the environment, such as Acinetobacter spp. Strategies that allow a reduction of pathogens from hospital envi...

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Autores principales: Blehm, Cláudia Justin, Monteiro, Marina Silveira Gregis, Bessa, Marjo Cadó, Leyser, Mariana, Dias, Amanda Simão, Sumienski, Juliana, Gallo, Stephanie Wagner, da Silva, Anelise Baptista, Barros, Andressa, Marco, Roberta, Preve, Camila Piuco, Ferreira, Carlos Alexandre Sanchez, Ramos, Fabiano, de Oliveira, Sílvia Dias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9684398/
https://www.ncbi.nlm.nih.gov/pubmed/36417032
http://dx.doi.org/10.1186/s13568-022-01491-x
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author Blehm, Cláudia Justin
Monteiro, Marina Silveira Gregis
Bessa, Marjo Cadó
Leyser, Mariana
Dias, Amanda Simão
Sumienski, Juliana
Gallo, Stephanie Wagner
da Silva, Anelise Baptista
Barros, Andressa
Marco, Roberta
Preve, Camila Piuco
Ferreira, Carlos Alexandre Sanchez
Ramos, Fabiano
de Oliveira, Sílvia Dias
author_facet Blehm, Cláudia Justin
Monteiro, Marina Silveira Gregis
Bessa, Marjo Cadó
Leyser, Mariana
Dias, Amanda Simão
Sumienski, Juliana
Gallo, Stephanie Wagner
da Silva, Anelise Baptista
Barros, Andressa
Marco, Roberta
Preve, Camila Piuco
Ferreira, Carlos Alexandre Sanchez
Ramos, Fabiano
de Oliveira, Sílvia Dias
author_sort Blehm, Cláudia Justin
collection PubMed
description Healthcare-associated infections (HAIs) represent a global challenge and an even more staggering concern when related to microorganisms capable of resisting and surviving for long periods in the environment, such as Acinetobacter spp. Strategies that allow a reduction of pathogens from hospital environments represent an additional barrier in infection control protocols, minimizing transmission to hospitalized patients. Considering the antimicrobial properties of copper, here, the bacterial load and the presence of Acinetobacter spp. were monitored on high handling surfaces covered by 99.9% copper films on intensive and non-intensive care unit bedrooms in a tertiary care hospital. Firstly, copper-coated films were able to inhibit the adhesion and biofilm formation of A. baumannii strains in in vitro assays. On the other hand, Acinetobacter spp. were isolated from both copper-coated and uncoated surfaces in the hospital, although the majority was detected on surfaces without copper. All carbapenem-resistant A. baumannii isolates identified harbored the bla(oxa-23) gene, while the A. nosocomialis isolates were susceptible to most antimicrobials tested. All isolates were susceptible to polymyxin B. Regarding the total aerobic bacteria, surfaces with copper-coated films presented lower total loads than those detected for controls. Copper coating films may be a workable strategy to mitigate HAIs, given their potential in reducing bacterial loads in nosocomial environments, including threatening pathogens like A. baumannii.
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spelling pubmed-96843982022-11-29 Copper-coated hospital surfaces: reduction of total bacterial loads and resistant Acinetobacter spp. Blehm, Cláudia Justin Monteiro, Marina Silveira Gregis Bessa, Marjo Cadó Leyser, Mariana Dias, Amanda Simão Sumienski, Juliana Gallo, Stephanie Wagner da Silva, Anelise Baptista Barros, Andressa Marco, Roberta Preve, Camila Piuco Ferreira, Carlos Alexandre Sanchez Ramos, Fabiano de Oliveira, Sílvia Dias AMB Express Original Article Healthcare-associated infections (HAIs) represent a global challenge and an even more staggering concern when related to microorganisms capable of resisting and surviving for long periods in the environment, such as Acinetobacter spp. Strategies that allow a reduction of pathogens from hospital environments represent an additional barrier in infection control protocols, minimizing transmission to hospitalized patients. Considering the antimicrobial properties of copper, here, the bacterial load and the presence of Acinetobacter spp. were monitored on high handling surfaces covered by 99.9% copper films on intensive and non-intensive care unit bedrooms in a tertiary care hospital. Firstly, copper-coated films were able to inhibit the adhesion and biofilm formation of A. baumannii strains in in vitro assays. On the other hand, Acinetobacter spp. were isolated from both copper-coated and uncoated surfaces in the hospital, although the majority was detected on surfaces without copper. All carbapenem-resistant A. baumannii isolates identified harbored the bla(oxa-23) gene, while the A. nosocomialis isolates were susceptible to most antimicrobials tested. All isolates were susceptible to polymyxin B. Regarding the total aerobic bacteria, surfaces with copper-coated films presented lower total loads than those detected for controls. Copper coating films may be a workable strategy to mitigate HAIs, given their potential in reducing bacterial loads in nosocomial environments, including threatening pathogens like A. baumannii. Springer Berlin Heidelberg 2022-11-23 /pmc/articles/PMC9684398/ /pubmed/36417032 http://dx.doi.org/10.1186/s13568-022-01491-x Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Original Article
Blehm, Cláudia Justin
Monteiro, Marina Silveira Gregis
Bessa, Marjo Cadó
Leyser, Mariana
Dias, Amanda Simão
Sumienski, Juliana
Gallo, Stephanie Wagner
da Silva, Anelise Baptista
Barros, Andressa
Marco, Roberta
Preve, Camila Piuco
Ferreira, Carlos Alexandre Sanchez
Ramos, Fabiano
de Oliveira, Sílvia Dias
Copper-coated hospital surfaces: reduction of total bacterial loads and resistant Acinetobacter spp.
title Copper-coated hospital surfaces: reduction of total bacterial loads and resistant Acinetobacter spp.
title_full Copper-coated hospital surfaces: reduction of total bacterial loads and resistant Acinetobacter spp.
title_fullStr Copper-coated hospital surfaces: reduction of total bacterial loads and resistant Acinetobacter spp.
title_full_unstemmed Copper-coated hospital surfaces: reduction of total bacterial loads and resistant Acinetobacter spp.
title_short Copper-coated hospital surfaces: reduction of total bacterial loads and resistant Acinetobacter spp.
title_sort copper-coated hospital surfaces: reduction of total bacterial loads and resistant acinetobacter spp.
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9684398/
https://www.ncbi.nlm.nih.gov/pubmed/36417032
http://dx.doi.org/10.1186/s13568-022-01491-x
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