SMARCC2 mediates the regulation of DKK1 by the transcription factor EGR1 through chromatin remodeling to reduce the proliferative capacity of glioblastoma

Switch/sucrose-nonfermenting (SWI/SNF) complexes play a key role in chromatin remodeling. Recent studies have found that SMARCC2, as the core subunit of the fundamental module of the complex, plays a key role in its early assembly. In this study, we found a unique function of SMARCC2 in inhibiting t...

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Detalles Bibliográficos
Autores principales: Li, Chiyang, Wang, Tong, Gu, Junwei, Qi, Songtao, Li, Junjie, Chen, Lei, Wu, Hang, Shi, Linyong, Song, Chong, Li, Hong, Zhu, Liwen, Lu, Yuntao, Zhou, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9684443/
https://www.ncbi.nlm.nih.gov/pubmed/36418306
http://dx.doi.org/10.1038/s41419-022-05439-8

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