LINC00924-induced fatty acid metabolic reprogramming facilitates gastric cancer peritoneal metastasis via hnRNPC-regulated alternative splicing of Mnk2

The molecular mechanism underlying gastric cancer (GC) peritoneal metastasis (PM) remains unclear. Here, we identified LINC00924 as a GC PM-related lncRNA through Microarray sequencing. LINC00924 was highly expressed in GC, and its high expression is associated with a broad range of PM. Via RNA sequ...

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Detalles Bibliográficos
Autores principales: He, Qiuming, Yang, Chaogang, Xiang, Zhenxian, Huang, Guoquan, Wu, Haitao, Chen, Tingna, Dou, Rongzhang, Song, Jialing, Han, Lei, Song, TianTian, Wang, Shuyi, Xiong, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9684446/
https://www.ncbi.nlm.nih.gov/pubmed/36418856
http://dx.doi.org/10.1038/s41419-022-05436-x

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