The systemic renin-angiotensin system in COVID-19

SARS-CoV-2 gains cell entry via angiotensin-converting enzyme (ACE) 2, a membrane-bound enzyme of the “alternative” (alt) renin-angiotensin system (RAS). ACE2 counteracts angiotensin II by converting it to potentially protective angiotensin 1–7. Using mass spectrometry, we assessed key metabolites o...

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Detalles Bibliográficos
Autores principales: Reindl-Schwaighofer, Roman, Hödlmoser, Sebastian, Domenig, Oliver, Krenn, Katharina, Eskandary, Farsad, Krenn, Simon, Schörgenhofer, Christian, Rumpf, Benedikt, Karolyi, Mario, Traugott, Marianna T., Abrahamowicz, Agnes, Tinhof, Viktoria, Mayfurth, Hannah, Rathkolb, Vincent, Mußnig, Sebastian, Schmölz, Lukas, Ullrich, Roman, Heinzel, Andreas, König, Franz, Binder, Christina, Bonderman, Diana, Strassl, Robert, Puchhammer-Stöckl, Elisabeth, Gorkiewicz, Gregor, Aberle, Judith H., Jilma, Bernd, Wenisch, Christoph, Poglitsch, Marko, Oberbauer, Rainer, Zoufaly, Alexander, Hecking, Manfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9684482/
https://www.ncbi.nlm.nih.gov/pubmed/36418458
http://dx.doi.org/10.1038/s41598-022-24628-1

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