Multi-omics analysis identifies osteosarcoma subtypes with distinct prognosis indicating stratified treatment

Osteosarcoma (OS) is a primary malignant bone tumor that most commonly affects children, adolescents, and young adults. Here, we comprehensively analyze genomic, epigenomic and transcriptomic data from 121 OS patients. Somatic mutations are diverse within the cohort, and only TP53 is significantly m...

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Detalles Bibliográficos
Autores principales: Jiang, Yafei, Wang, Jinzeng, Sun, Mengxiong, Zuo, Dongqing, Wang, Hongsheng, Shen, Jiakang, Jiang, Wenyan, Mu, Haoran, Ma, Xiaojun, Yin, Fei, Lin, Jun, Wang, Chongren, Yu, Shuting, Jiang, Lu, Lv, Gang, Liu, Feng, Xue, Linghang, Tian, Kai, Wang, Gangyang, Zhou, Zifei, Lv, Yu, Wang, Zhuoying, Zhang, Tao, Xu, Jing, Yang, Liu, Zhao, Kewen, Sun, Wei, Tang, Yujie, Cai, Zhengdong, Wang, Shengyue, Hua, Yingqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9684515/
https://www.ncbi.nlm.nih.gov/pubmed/36418292
http://dx.doi.org/10.1038/s41467-022-34689-5

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