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A mass spectrometry-based approach for the identification of Kpnβ1 binding partners in cancer cells

Karyopherin beta 1 (Kpnβ1) is the principal nuclear importer of cargo proteins and plays a role in many cellular processes. Its expression is upregulated in cancer and essential for cancer cell viability, thus the identification of its binding partners might help in the discovery of anti-cancer ther...

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Detalles Bibliográficos
Autores principales: Okpara, Michael O., Hermann, Clemens, van der Watt, Pauline J., Garnett, Shaun, Blackburn, Jonathan M., Leaner, Virna D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9684564/
https://www.ncbi.nlm.nih.gov/pubmed/36418423
http://dx.doi.org/10.1038/s41598-022-24194-6