Downregulating PDPK1 and taking phillyrin as PDPK1-targeting drug protect hepatocytes from alcoholic steatohepatitis by promoting autophagy

The health risk stemming from drinking alcohol is serious, sometimes even life-threatening. Alcoholic steatohepatitis (ASH) is a critical stage leading to cirrhosis and end-stage liver disease. However, its pathogenesis is still far from clearly understood, and a treatment that is widely recognised...

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Detalles Bibliográficos
Autores principales: Zhang, Yuan, Ding, Yuhao, Zhao, Huizi, Wang, Zhonghao, Zeng, Fanle, Qian, Zhenzhen, Li, Jun, Ma, Taotao, Huang, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9684571/
https://www.ncbi.nlm.nih.gov/pubmed/36418288
http://dx.doi.org/10.1038/s41419-022-05422-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9684571/
https://www.ncbi.nlm.nih.gov/pubmed/36418288
http://dx.doi.org/10.1038/s41419-022-05422-3

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