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Plasma cell but not CD20-mediated B-cell depletion protects from bleomycin-induced lung fibrosis
Idiopathic pulmonary fibrosis (IPF) is an interstitial lung disease associated with chronic inflammation and tissue remodelling leading to fibrosis, reduced pulmonary function, respiratory failure and death. Bleomycin (Blm)-induced lung fibrosis in mice replicates several clinical features of human...
Autores principales: | Prêle, Cecilia M., Miles, Tylah, Pearce, David R., O'Donoghue, Robert J., Grainge, Chris, Barrett, Lucy, Birnie, Kimberly, Lucas, Andrew D., Baltic, Svetlana, Ernst, Matthias, Rinaldi, Catherine, Laurent, Geoffrey J., Knight, Darryl A., Fear, Mark, Hoyne, Gerard, McAnulty, Robin J., Mutsaers, Steven E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
European Respiratory Society
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9684624/ https://www.ncbi.nlm.nih.gov/pubmed/35798357 http://dx.doi.org/10.1183/13993003.01469-2021 |
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