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Acquired Hemophilia in an Elderly Patient with Non-Small Cell Lung Cancer: a Case Report

Acquired hemophilia A (AHA) is a rare autoimmune disease caused by autoantibodies against coagulation factor VIII and characterized by spontaneous hemorrhage in patients with no previous family or personal history of bleeding. We report here a case of AHA that occurred in the Department of Medicina...

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Autores principales: Dulcetti, Antonio, Bruscia, C., Malena, D. M., Benvenuto, R., Martocchia, A., Sentimentale, A., Tafaro, L., March, M. Rocchietti, Martelletti, P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9684743/
https://www.ncbi.nlm.nih.gov/pubmed/36466121
http://dx.doi.org/10.1007/s42399-022-01330-x
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author Dulcetti, Antonio
Bruscia, C.
Malena, D. M.
Benvenuto, R.
Martocchia, A.
Sentimentale, A.
Tafaro, L.
March, M. Rocchietti
Martelletti, P.
author_facet Dulcetti, Antonio
Bruscia, C.
Malena, D. M.
Benvenuto, R.
Martocchia, A.
Sentimentale, A.
Tafaro, L.
March, M. Rocchietti
Martelletti, P.
author_sort Dulcetti, Antonio
collection PubMed
description Acquired hemophilia A (AHA) is a rare autoimmune disease caused by autoantibodies against coagulation factor VIII and characterized by spontaneous hemorrhage in patients with no previous family or personal history of bleeding. We report here a case of AHA that occurred in the Department of Medicina D’Urgenza in Sant’Andrea Hospital in a patient with previous diagnosis of NSLC. The aim of this article is to allow a more comprehensive knowledge of AHA that both for the rarity and the poor literature is underdiagnosed; for all these reasons, it is important that different specialists, like emergency specialists, experts in internal medicine, hematologists, and oncologists, acquire a more complete knowledge of the clinical and laboratory features of this disease, allowing an early diagnosis crucial for the evolution of the coagulopathy.
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spelling pubmed-96847432022-11-28 Acquired Hemophilia in an Elderly Patient with Non-Small Cell Lung Cancer: a Case Report Dulcetti, Antonio Bruscia, C. Malena, D. M. Benvenuto, R. Martocchia, A. Sentimentale, A. Tafaro, L. March, M. Rocchietti Martelletti, P. SN Compr Clin Med Case Report Acquired hemophilia A (AHA) is a rare autoimmune disease caused by autoantibodies against coagulation factor VIII and characterized by spontaneous hemorrhage in patients with no previous family or personal history of bleeding. We report here a case of AHA that occurred in the Department of Medicina D’Urgenza in Sant’Andrea Hospital in a patient with previous diagnosis of NSLC. The aim of this article is to allow a more comprehensive knowledge of AHA that both for the rarity and the poor literature is underdiagnosed; for all these reasons, it is important that different specialists, like emergency specialists, experts in internal medicine, hematologists, and oncologists, acquire a more complete knowledge of the clinical and laboratory features of this disease, allowing an early diagnosis crucial for the evolution of the coagulopathy. Springer International Publishing 2022-11-23 2023 /pmc/articles/PMC9684743/ /pubmed/36466121 http://dx.doi.org/10.1007/s42399-022-01330-x Text en © The Author(s) 2022, corrected publication 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Case Report
Dulcetti, Antonio
Bruscia, C.
Malena, D. M.
Benvenuto, R.
Martocchia, A.
Sentimentale, A.
Tafaro, L.
March, M. Rocchietti
Martelletti, P.
Acquired Hemophilia in an Elderly Patient with Non-Small Cell Lung Cancer: a Case Report
title Acquired Hemophilia in an Elderly Patient with Non-Small Cell Lung Cancer: a Case Report
title_full Acquired Hemophilia in an Elderly Patient with Non-Small Cell Lung Cancer: a Case Report
title_fullStr Acquired Hemophilia in an Elderly Patient with Non-Small Cell Lung Cancer: a Case Report
title_full_unstemmed Acquired Hemophilia in an Elderly Patient with Non-Small Cell Lung Cancer: a Case Report
title_short Acquired Hemophilia in an Elderly Patient with Non-Small Cell Lung Cancer: a Case Report
title_sort acquired hemophilia in an elderly patient with non-small cell lung cancer: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9684743/
https://www.ncbi.nlm.nih.gov/pubmed/36466121
http://dx.doi.org/10.1007/s42399-022-01330-x
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