Cargando…

A data-driven spatially-specific vaccine allocation framework for COVID-19

Although coronavirus disease 2019 (COVID-19) vaccines have been introduced, their allocation is a challenging problem. We propose a data-driven, spatially-specific vaccine allocation framework that aims to minimize the number of COVID-19-related deaths or infections. The framework combines a regiona...

Descripción completa

Detalles Bibliográficos
Autores principales: Hong, Zhaofu, Li, Yingjie, Gong, Yeming, Chen, Wanying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9684883/
https://www.ncbi.nlm.nih.gov/pubmed/36467001
http://dx.doi.org/10.1007/s10479-022-05037-z
_version_ 1784835386207371264
author Hong, Zhaofu
Li, Yingjie
Gong, Yeming
Chen, Wanying
author_facet Hong, Zhaofu
Li, Yingjie
Gong, Yeming
Chen, Wanying
author_sort Hong, Zhaofu
collection PubMed
description Although coronavirus disease 2019 (COVID-19) vaccines have been introduced, their allocation is a challenging problem. We propose a data-driven, spatially-specific vaccine allocation framework that aims to minimize the number of COVID-19-related deaths or infections. The framework combines a regional risk-level classification model solved by a self-organizing map neural network, a spatially-specific disease progression model, and a vaccine allocation model that considers vaccine production capacity. We use data obtained from Wuhan and 35 other cities in China from January 26 to February 11, 2020, to avoid the effects of intervention. Our results suggest that, in region-wise distribution of vaccines, they should be allocated first to the source region of the outbreak and then to the other regions in order of decreasing risk whether the outcome measure is the number of deaths or infections. This spatially-specific vaccine allocation policy significantly outperforms some current allocation policies.
format Online
Article
Text
id pubmed-9684883
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Springer US
record_format MEDLINE/PubMed
spelling pubmed-96848832022-11-28 A data-driven spatially-specific vaccine allocation framework for COVID-19 Hong, Zhaofu Li, Yingjie Gong, Yeming Chen, Wanying Ann Oper Res Original Research Although coronavirus disease 2019 (COVID-19) vaccines have been introduced, their allocation is a challenging problem. We propose a data-driven, spatially-specific vaccine allocation framework that aims to minimize the number of COVID-19-related deaths or infections. The framework combines a regional risk-level classification model solved by a self-organizing map neural network, a spatially-specific disease progression model, and a vaccine allocation model that considers vaccine production capacity. We use data obtained from Wuhan and 35 other cities in China from January 26 to February 11, 2020, to avoid the effects of intervention. Our results suggest that, in region-wise distribution of vaccines, they should be allocated first to the source region of the outbreak and then to the other regions in order of decreasing risk whether the outcome measure is the number of deaths or infections. This spatially-specific vaccine allocation policy significantly outperforms some current allocation policies. Springer US 2022-11-22 /pmc/articles/PMC9684883/ /pubmed/36467001 http://dx.doi.org/10.1007/s10479-022-05037-z Text en © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2022, Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Original Research
Hong, Zhaofu
Li, Yingjie
Gong, Yeming
Chen, Wanying
A data-driven spatially-specific vaccine allocation framework for COVID-19
title A data-driven spatially-specific vaccine allocation framework for COVID-19
title_full A data-driven spatially-specific vaccine allocation framework for COVID-19
title_fullStr A data-driven spatially-specific vaccine allocation framework for COVID-19
title_full_unstemmed A data-driven spatially-specific vaccine allocation framework for COVID-19
title_short A data-driven spatially-specific vaccine allocation framework for COVID-19
title_sort data-driven spatially-specific vaccine allocation framework for covid-19
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9684883/
https://www.ncbi.nlm.nih.gov/pubmed/36467001
http://dx.doi.org/10.1007/s10479-022-05037-z
work_keys_str_mv AT hongzhaofu adatadrivenspatiallyspecificvaccineallocationframeworkforcovid19
AT liyingjie adatadrivenspatiallyspecificvaccineallocationframeworkforcovid19
AT gongyeming adatadrivenspatiallyspecificvaccineallocationframeworkforcovid19
AT chenwanying adatadrivenspatiallyspecificvaccineallocationframeworkforcovid19
AT hongzhaofu datadrivenspatiallyspecificvaccineallocationframeworkforcovid19
AT liyingjie datadrivenspatiallyspecificvaccineallocationframeworkforcovid19
AT gongyeming datadrivenspatiallyspecificvaccineallocationframeworkforcovid19
AT chenwanying datadrivenspatiallyspecificvaccineallocationframeworkforcovid19