Cargando…

Inhibition of colorectal cancer tumorigenesis by ursolic acid and doxorubicin is mediated by targeting the Akt signaling pathway and activating the Hippo signaling pathway

Colorectal cancer (CRC) is one of the deadliest malignant tumors worldwide and its prevalence is increasing in South Korea. The efficacy of combined treatment with natural product-derived and chemotherapy agents including curcumin combined with 5-fluorouracil, resveratrol combined with cisplatin and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hu, Dan, Meng, Ruo Yu, Nguyen, Thi Van, Chai, Ok Hee, Park, Byung Hyun, Lee, Ju-Seog, Kim, Soo Mi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2022
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9685224/ https://www.ncbi.nlm.nih.gov/pubmed/36382656 http://dx.doi.org/10.3892/mmr.2022.12898

Ejemplares similares

Inhibition of the interaction between Hippo/YAP and Akt signaling with ursolic acid and 3′3-diindolylmethane suppresses esophageal cancer tumorigenesis
por: Meng, Ruo Yu, et al.
Publicado: (2023)

Activating Hippo Pathway via Rassf1 by Ursolic Acid Suppresses the Tumorigenesis of Gastric Cancer
por: Kim, Seong-Hun, et al.
Publicado: (2019)

Ursolic Acid Accelerates Paclitaxel-Induced Cell Death in Esophageal Cancer Cells by Suppressing Akt/FOXM1 Signaling Cascade
por: Meng, Ruo Yu, et al.
Publicado: (2021)

Interaction of the Hippo Pathway and Phosphatases in Tumorigenesis
por: Sarmasti Emami, Sahar, et al.
Publicado: (2020)

Hippo Signaling Pathway in Gliomas
por: Masliantsev, Konstantin, et al.
Publicado: (2021)

Hippo Signaling Pathway as a Central Mediator of Receptors Tyrosine Kinases (RTKs) in Tumorigenesis
por: Azad, Taha, et al.
Publicado: (2020)

The role of the Hippo pathway in human disease and tumorigenesis
por: Barron, Daniel A, et al.
Publicado: (2014)

Down-Regulation of AKT Signalling by Ursolic Acid Induces Intrinsic Apoptosis and Sensitization to Doxorubicin in Soft Tissue Sarcoma
por: Villar, Victor Hugo, et al.
Publicado: (2016)

PTEN lipid phosphatase inactivation links the hippo and PI3K/Akt pathways to induce gastric tumorigenesis
por: Xu, Wenting, et al.
Publicado: (2018)

The Hippo signaling pathway: from multiple signals to the hallmarks of cancers: Hippo pathway: from multiple signals to the hallmarks of cancers
por: Zhu, Ning, et al.
Publicado: (2023)

Physiological and pathological roles of the Hippo‐YAP/TAZ signaling pathway in liver formation, homeostasis, and tumorigenesis
por: Nishina, Hiroshi
Publicado: (2022)

Hippo signaling pathway and respiratory diseases
por: Tang, Weifeng, et al.
Publicado: (2022)

Hippo Signaling Pathway in Pancreas Development
por: Wu, Yifan, et al.
Publicado: (2021)

The Hippo pathway mediates Semaphorin signaling
por: Meng, Zhipeng, et al.
Publicado: (2022)

Hsa_circ_0005273 facilitates breast cancer tumorigenesis by regulating YAP1-hippo signaling pathway
por: Wang, Xuehui, et al.
Publicado: (2021)

The Hippo signaling pathway in gastric cancer: Targeting Hippo for GC treatment
por: Cao, Zhifa, et al.
Publicado: (2023)

Cucurbitacin B Inhibits the Hippo-YAP Signaling Pathway and Exerts Anticancer Activity in Colorectal Cancer Cells
por: Chai, Yanting, et al.
Publicado: (2018)

Zyxin Links Fat Signaling to the Hippo Pathway
por: Rauskolb, Cordelia, et al.
Publicado: (2011)

The Spectrin cytoskeleton regulates the Hippo signalling pathway
por: Fletcher, Georgina C, et al.
Publicado: (2015)

Regulation of the Hippo signaling pathway by ubiquitin modification
por: Kim, Youngeun, et al.
Publicado: (2018)

The Hippo Signaling Pathway in Cardiac Development and Diseases
por: Mia, Masum M., et al.
Publicado: (2019)

The Hippo Signaling Pathway in Drug Resistance in Cancer
por: Zeng, Renya, et al.
Publicado: (2021)

The Hippo Signaling Pathway: The Trader of Tumor Microenvironment
por: Yang, Duo, et al.
Publicado: (2021)

Inactivation of the Akt/FOXM1 Signaling Pathway by Panobinostat Suppresses the Proliferation and Metastasis of Gastric Cancer Cells
por: Lee, Na-Ri, et al.
Publicado: (2021)

Correction to: Hsa_circ_0005273 facilitates breast cancer tumorigenesis by regulating YAP1-hippo signaling pathway
por: Wang, Xuehui, et al.
Publicado: (2021)

Retracted: Cucurbitacin B Inhibits the Hippo-YAP Signaling Pathway and Exerts Anticancer Activity in Colorectal Cancer Cells
por: Chai, Yanting, et al.
Publicado: (2022)

The Hippo signaling pathway provides novel anti-cancer drug targets
por: Bae, June Sung, et al.
Publicado: (2016)

miR-1307-5p suppresses proliferation and tumorigenesis of bladder cancer via targeting MDM4 and the Hippo signaling pathway
por: Huang, Wei, et al.
Publicado: (2022)

Cyclovirobuxine D inhibits colorectal cancer tumorigenesis via the CTHRC1-AKT/ERK-Snail signaling pathway
por: Jiang, Fengqi, et al.
Publicado: (2020)

Synergistic effect of YOD1 and USP21 on the Hippo signaling pathway
por: Park, Sang-Soo, et al.
Publicado: (2023)

The Hippo-Salvador signaling pathway regulates renal tubulointerstitial fibrosis
por: Seo, Eunjeong, et al.
Publicado: (2016)

Expression of Hippo Pathway in Colorectal Cancer
por: Liang, Kun, et al.
Publicado: (2014)

Mob Family Proteins: Regulatory Partners in Hippo and Hippo-Like Intracellular Signaling Pathways
por: Duhart, Juan Carlos, et al.
Publicado: (2020)

Signal integration in TGF-β, WNT, and Hippo pathways
por: Attisano, Liliana, et al.
Publicado: (2013)

Hippo/YAP signaling pathway is involved in osteosarcoma chemoresistance
por: Wang, Dong-Yu, et al.
Publicado: (2016)

Regulation of Tissue Growth by the Mammalian Hippo Signaling Pathway
por: Watt, Kevin I., et al.
Publicado: (2017)

Emerging role of Hippo signalling pathway in bladder cancer
por: Xia, Jianling, et al.
Publicado: (2017)

The role of Hippo signal pathway in breast cancer metastasis
por: Wei, Changran, et al.
Publicado: (2018)

New Therapeutic Approach for Targeting Hippo Signalling Pathway
por: Dominguez-Berrocal, Leticia, et al.
Publicado: (2019)

Hippo signaling pathway is altered in Duchenne muscular dystrophy
por: Vita, Gian Luca, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_3m6g1bh6b1jb875rml6oo04tru