Loss of CD24 promotes radiation- and chemo-resistance by inducing stemness properties associated with a hybrid E/M state in breast cancer cells

Cancer stem cells (CSCs) serve an essential role in failure of conventional antitumor therapy. In breast cancer, CD24(−/low)/CD44(+) phenotype and high aldehyde dehydrogenase activity are associated with CSC subtypes. Furthermore, CD24(−/low)/CD44(+) pattern is also characteristic of mesenchymal cel...

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Detalles Bibliográficos
Autores principales: Bontemps, Isaline, Lallemand, Celine, Biard, Denis, Dechamps, Nathalie, Kortulewski, Thierry, Bourneuf, Emmanuelle, Siberchicot, Capucine, Boussin, François, Chevillard, Sylvie, Campalans, Anna, Lebeau, Jerome
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9685273/
https://www.ncbi.nlm.nih.gov/pubmed/36367190
http://dx.doi.org/10.3892/or.2022.8441

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