Full of twists and turns: Collecting duct carcinoma presenting as persistent cough

We report a case of collecting duct carcinoma (CDC) in a 60-year-old man who presented with persistent cough, low back pain, and weight loss. Contrast-enhanced CT of chest and abdomen revealed a mass in the medulla of the middle and upper parts of the right kidney, with spread into perirenal tissue,...

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Detalles Bibliográficos
Autores principales: Li, Xueying, Shen, Zhiyong, Han, Yu, Duan, Qinghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9685280/
https://www.ncbi.nlm.nih.gov/pubmed/36438456
http://dx.doi.org/10.1016/j.eucr.2022.102283
Descripción
Sumario:We report a case of collecting duct carcinoma (CDC) in a 60-year-old man who presented with persistent cough, low back pain, and weight loss. Contrast-enhanced CT of chest and abdomen revealed a mass in the medulla of the middle and upper parts of the right kidney, with spread into perirenal tissue, vascular invasion, and distant metastasis. First renal biopsy only showed inflammation. Repeat biopsy and histopathological examination and immunohistochemistry confirmed CDC. The patient died 2 months after diagnosis despite interventional therapy, chemotherapy, and targeted therapy. This case is being reported because of its rarity and unusual presentation.

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