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Rapidly growing proliferative pulmonary chondroma: A case report

INTRODUCTION: Pulmonary chondroma, a component of Carney's triad, is commonly unilateral and multiple, and progresses slowly. Herein, we report a case of a chondrogenic tumour that grew and proliferated during follow-up. PRESENTATION OF CASE: A female patient in her 20s presenting with a cough...

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Autores principales: Uchida, Tsuyoshi, Matsubara, Hirochika, Muto, Mamoru, Sugimura, Aya, Onuki, Yuichiro, Nakajima, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9685284/
https://www.ncbi.nlm.nih.gov/pubmed/36434873
http://dx.doi.org/10.1016/j.ijscr.2022.107776
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author Uchida, Tsuyoshi
Matsubara, Hirochika
Muto, Mamoru
Sugimura, Aya
Onuki, Yuichiro
Nakajima, Hiroyuki
author_facet Uchida, Tsuyoshi
Matsubara, Hirochika
Muto, Mamoru
Sugimura, Aya
Onuki, Yuichiro
Nakajima, Hiroyuki
author_sort Uchida, Tsuyoshi
collection PubMed
description INTRODUCTION: Pulmonary chondroma, a component of Carney's triad, is commonly unilateral and multiple, and progresses slowly. Herein, we report a case of a chondrogenic tumour that grew and proliferated during follow-up. PRESENTATION OF CASE: A female patient in her 20s presenting with a cough was found to have a 1.4-cm nodule in the left lung on computed tomography (CT). After 18 months' follow-up, CT revealed that the original nodule had increased to 2.2 cm, and a new 1.3-cm nodule had appeared. She was then referred to our hospital and underwent a robot-assisted lower lobectomy of the left lung. The tumour was diagnosed as a chondrogenic tumour. She had no problems after the surgery or during follow-up; other signs of the Carney's triad were ruled out. Twenty-six months postoperatively, there was no evidence of recurrence. DISCUSSION: One report suggests that the growth of pulmonary chondroma is slow, but the present case showed an increase in both the size and number of tumours within 2 years without any symptoms. The chondroma did not recur after the surgery, though her pulmonary tumours had grown and proliferated rapidly. Furthermore, it has been reported that an average of 8.4 years is needed for another sign of Carney's triad to appear; therefore, careful follow-up should be continued. CONCLUSION: This report suggests that pulmonary chondroma can grow and proliferate rapidly and asymptomatically, and can be controlled by complete resection.
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spelling pubmed-96852842022-11-25 Rapidly growing proliferative pulmonary chondroma: A case report Uchida, Tsuyoshi Matsubara, Hirochika Muto, Mamoru Sugimura, Aya Onuki, Yuichiro Nakajima, Hiroyuki Int J Surg Case Rep Case Report INTRODUCTION: Pulmonary chondroma, a component of Carney's triad, is commonly unilateral and multiple, and progresses slowly. Herein, we report a case of a chondrogenic tumour that grew and proliferated during follow-up. PRESENTATION OF CASE: A female patient in her 20s presenting with a cough was found to have a 1.4-cm nodule in the left lung on computed tomography (CT). After 18 months' follow-up, CT revealed that the original nodule had increased to 2.2 cm, and a new 1.3-cm nodule had appeared. She was then referred to our hospital and underwent a robot-assisted lower lobectomy of the left lung. The tumour was diagnosed as a chondrogenic tumour. She had no problems after the surgery or during follow-up; other signs of the Carney's triad were ruled out. Twenty-six months postoperatively, there was no evidence of recurrence. DISCUSSION: One report suggests that the growth of pulmonary chondroma is slow, but the present case showed an increase in both the size and number of tumours within 2 years without any symptoms. The chondroma did not recur after the surgery, though her pulmonary tumours had grown and proliferated rapidly. Furthermore, it has been reported that an average of 8.4 years is needed for another sign of Carney's triad to appear; therefore, careful follow-up should be continued. CONCLUSION: This report suggests that pulmonary chondroma can grow and proliferate rapidly and asymptomatically, and can be controlled by complete resection. Elsevier 2022-11-13 /pmc/articles/PMC9685284/ /pubmed/36434873 http://dx.doi.org/10.1016/j.ijscr.2022.107776 Text en © 2022 The Author(s) https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Uchida, Tsuyoshi
Matsubara, Hirochika
Muto, Mamoru
Sugimura, Aya
Onuki, Yuichiro
Nakajima, Hiroyuki
Rapidly growing proliferative pulmonary chondroma: A case report
title Rapidly growing proliferative pulmonary chondroma: A case report
title_full Rapidly growing proliferative pulmonary chondroma: A case report
title_fullStr Rapidly growing proliferative pulmonary chondroma: A case report
title_full_unstemmed Rapidly growing proliferative pulmonary chondroma: A case report
title_short Rapidly growing proliferative pulmonary chondroma: A case report
title_sort rapidly growing proliferative pulmonary chondroma: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9685284/
https://www.ncbi.nlm.nih.gov/pubmed/36434873
http://dx.doi.org/10.1016/j.ijscr.2022.107776
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