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Dennd5b-Deficient Mice are Resistant to PCSK9-Induced Hypercholesterolemia and Diet-Induced Hepatic Steatosis

Dennd5b plays a pivotal role in intestinal absorption of dietary lipids in mice and is associated with body mass index in humans. This study examined the impact of whole-body Dennd5b deletion on plasma lipid concentrations, atherosclerosis, and hepatic lipid metabolism in mice. Hypercholesterolemia...

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Detalles Bibliográficos
Autores principales:	Mobilia, Maura, Whitus, Callie, Karakashian, Alexander, Lu, Hong S., Daugherty, Alan, Gordon, Scott M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9685390/ https://www.ncbi.nlm.nih.gov/pubmed/36243100 http://dx.doi.org/10.1016/j.jlr.2022.100296

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