Activin A directly impairs human cardiomyocyte contractile function indicating a potential role in heart failure development

Activin A has been linked to cardiac dysfunction in aging and disease, with elevated circulating levels found in patients with hypertension, atherosclerosis, and heart failure. Here, we investigated whether Activin A directly impairs cardiomyocyte (CM) contractile function and kinetics utilizing cel...

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Detalles Bibliográficos
Autores principales: MacDonnell, Scott, Megna, Jake, Ruan, Qin, Zhu, Olivia, Halasz, Gabor, Jasewicz, Dan, Powers, Kristi, E, Hock, del Pilar Molina-Portela, Maria, Jin, Ximei, Zhang, Dongqin, Torello, Justin, Feric, Nicole T., Graziano, Michael P., Shekhar, Akshay, Dunn, Michael E., Glass, David, Morton, Lori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9685658/
https://www.ncbi.nlm.nih.gov/pubmed/36440002
http://dx.doi.org/10.3389/fcvm.2022.1038114

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