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Towards clinical implementation of circulating tumor DNA in metastatic prostate cancer: Opportunities for integration and pitfalls to interpretation

Plasma circulating tumor DNA (ctDNA) represents short fragments of tumor-derived DNA released into the bloodstream primarily from cancer cells undergoing apoptosis. In metastatic castration-resistant prostate cancer (mCRPC), characterizing genomic alterations in ctDNA identifies mutations, copy numb...

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Detalles Bibliográficos
Autores principales: Kwan, Edmond M., Wyatt, Alexander W., Chi, Kim N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9685669/
https://www.ncbi.nlm.nih.gov/pubmed/36439451
http://dx.doi.org/10.3389/fonc.2022.1054497

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