Whole-exome sequencing identifies novel protein-altering variants associated with serum apolipoprotein and lipid concentrations

BACKGROUND: Dyslipidemia is a major risk factor for cardiovascular disease, and diabetes impacts the lipid metabolism through multiple pathways. In addition to the standard lipid measurements, apolipoprotein concentrations provide added awareness of the burden of circulating lipoproteins. While comm...

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Detalles Bibliográficos
Autores principales: Sandholm, Niina, Hotakainen, Ronja, Haukka, Jani K., Jansson Sigfrids, Fanny, Dahlström, Emma H., Antikainen, Anni A., Valo, Erkka, Syreeni, Anna, Kilpeläinen, Elina, Kytölä, Anastasia, Palotie, Aarno, Harjutsalo, Valma, Forsblom, Carol, Groop, Per-Henrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9685920/
https://www.ncbi.nlm.nih.gov/pubmed/36419110
http://dx.doi.org/10.1186/s13073-022-01135-6

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