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Automatic detection of Covid-19 from chest X-ray and lung computed tomography images using deep neural networks and transfer learning

The world has been undergoing the most ever unprecedented circumstances caused by the coronavirus pandemic, which is having a devastating global effect in different aspects of life. Since there are not effective antiviral treatments for Covid-19 yet, it is crucial to early detect and monitor the pro...

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Autores principales: Duong, Linh T., Nguyen, Phuong T., Iovino, Ludovico, Flammini, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9686054/
https://www.ncbi.nlm.nih.gov/pubmed/36447954
http://dx.doi.org/10.1016/j.asoc.2022.109851
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author Duong, Linh T.
Nguyen, Phuong T.
Iovino, Ludovico
Flammini, Michele
author_facet Duong, Linh T.
Nguyen, Phuong T.
Iovino, Ludovico
Flammini, Michele
author_sort Duong, Linh T.
collection PubMed
description The world has been undergoing the most ever unprecedented circumstances caused by the coronavirus pandemic, which is having a devastating global effect in different aspects of life. Since there are not effective antiviral treatments for Covid-19 yet, it is crucial to early detect and monitor the progression of the disease, thereby helping to reduce mortality. While different measures are being used to combat the virus, medical imaging techniques have been examined to support doctors in diagnosing the disease. In this paper, we present a practical solution for the detection of Covid-19 from chest X-ray (CXR) and lung computed tomography (LCT) images, exploiting cutting-edge Machine Learning techniques. As the main classification engine, we make use of EfficientNet and MixNet, two recently developed families of deep neural networks. Furthermore, to make the training more effective and efficient, we apply three transfer learning algorithms. The ultimate aim is to build a reliable expert system to detect Covid-19 from different sources of images, making it be a multi-purpose AI diagnosing system. We validated our proposed approach using four real-world datasets. The first two are CXR datasets consist of 15,000 and 17,905 images, respectively. The other two are LCT datasets with 2,482 and 411,528 images, respectively. The five-fold cross-validation methodology was used to evaluate the approach, where the dataset is split into five parts, and accordingly the evaluation is conducted in five rounds. By each evaluation, four parts are combined to form the training data, and the remaining one is used for testing. We obtained an encouraging prediction performance for all the considered datasets. In all the configurations, the obtained accuracy is always larger than 95.0%. Compared to various existing studies, our approach yields a substantial performance gain. Moreover, such an improvement is statistically significant.
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spelling pubmed-96860542022-11-25 Automatic detection of Covid-19 from chest X-ray and lung computed tomography images using deep neural networks and transfer learning Duong, Linh T. Nguyen, Phuong T. Iovino, Ludovico Flammini, Michele Appl Soft Comput Article The world has been undergoing the most ever unprecedented circumstances caused by the coronavirus pandemic, which is having a devastating global effect in different aspects of life. Since there are not effective antiviral treatments for Covid-19 yet, it is crucial to early detect and monitor the progression of the disease, thereby helping to reduce mortality. While different measures are being used to combat the virus, medical imaging techniques have been examined to support doctors in diagnosing the disease. In this paper, we present a practical solution for the detection of Covid-19 from chest X-ray (CXR) and lung computed tomography (LCT) images, exploiting cutting-edge Machine Learning techniques. As the main classification engine, we make use of EfficientNet and MixNet, two recently developed families of deep neural networks. Furthermore, to make the training more effective and efficient, we apply three transfer learning algorithms. The ultimate aim is to build a reliable expert system to detect Covid-19 from different sources of images, making it be a multi-purpose AI diagnosing system. We validated our proposed approach using four real-world datasets. The first two are CXR datasets consist of 15,000 and 17,905 images, respectively. The other two are LCT datasets with 2,482 and 411,528 images, respectively. The five-fold cross-validation methodology was used to evaluate the approach, where the dataset is split into five parts, and accordingly the evaluation is conducted in five rounds. By each evaluation, four parts are combined to form the training data, and the remaining one is used for testing. We obtained an encouraging prediction performance for all the considered datasets. In all the configurations, the obtained accuracy is always larger than 95.0%. Compared to various existing studies, our approach yields a substantial performance gain. Moreover, such an improvement is statistically significant. Elsevier B.V. 2023-01 2022-11-24 /pmc/articles/PMC9686054/ /pubmed/36447954 http://dx.doi.org/10.1016/j.asoc.2022.109851 Text en © 2022 Elsevier B.V. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Duong, Linh T.
Nguyen, Phuong T.
Iovino, Ludovico
Flammini, Michele
Automatic detection of Covid-19 from chest X-ray and lung computed tomography images using deep neural networks and transfer learning
title Automatic detection of Covid-19 from chest X-ray and lung computed tomography images using deep neural networks and transfer learning
title_full Automatic detection of Covid-19 from chest X-ray and lung computed tomography images using deep neural networks and transfer learning
title_fullStr Automatic detection of Covid-19 from chest X-ray and lung computed tomography images using deep neural networks and transfer learning
title_full_unstemmed Automatic detection of Covid-19 from chest X-ray and lung computed tomography images using deep neural networks and transfer learning
title_short Automatic detection of Covid-19 from chest X-ray and lung computed tomography images using deep neural networks and transfer learning
title_sort automatic detection of covid-19 from chest x-ray and lung computed tomography images using deep neural networks and transfer learning
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9686054/
https://www.ncbi.nlm.nih.gov/pubmed/36447954
http://dx.doi.org/10.1016/j.asoc.2022.109851
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