Exosomal lncRNA HOTAIR induce macrophages to M2 polarization via PI3K/ p-AKT /AKT pathway and promote EMT and metastasis in laryngeal squamous cell carcinoma

Exosomes are a new way of the communication between the tumor cell and macrophage in the micro-environment. The macrophage can be induced to different phenotypes according to the different tumors. In the present study, long-chain noncoding RNA HOTAIR (lncRNA HOTAIR) was highly expressed in LSCC and...

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Detalles Bibliográficos
Autores principales: Wang, Jingting, Wang, Nan, Zheng, Zeyu, Che, Yanlu, Suzuki, Masanobu, Kano, Satoshi, Lu, Jianguang, Wang, Peng, Sun, Yanan, Homma, Akihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9686105/
https://www.ncbi.nlm.nih.gov/pubmed/36424539
http://dx.doi.org/10.1186/s12885-022-10210-5

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