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An altered transcriptome underlies cln5-deficiency phenotypes in Dictyostelium discoideum
Mutations in CLN5 cause a subtype of neuronal ceroid lipofuscinosis (NCL) called CLN5 disease. The NCLs, commonly referred to as Batten disease, are a family of neurodegenerative lysosomal storage diseases that affect all ages and ethnicities globally. Previous research showed that CLN5 participates...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9686302/ https://www.ncbi.nlm.nih.gov/pubmed/36437924 http://dx.doi.org/10.3389/fgene.2022.1045738 |